...Antonello E. Rigamonti; Alessandro Sartorio; Pasquale Scognamiglio; Silvia Bini; Alessio M. Monteleone; Daniele Mastromo; Nicoletta Marazzi; Silvano G. Cella; Palmiero Monteleone Objective: Patients with bulimia nervosa (BN) are reported to have decreased postprandial levels of cholecystokinin (CCK...

...Reinhard Pietrowsky; Sebastian Rudolf; Matthias Mölle; Horst L. Fehm; Jan Born Cholecystokinin (CCK)-like peptides, such as ceruletide, have been found to improve selective attention as indicated by the processing negativity (PN) of the event-related brain potential. The present study compared...

...R. Pietrowsky; H.L. Fehm; A. Er; B. Bathelt; J. Born Two experiments are reported, investigating the effects of the cholecystokinin analog ceruletide on central nervous activation in man. In experiment I, 0.55 μg/h ceruletide was infused at a constant rate during the night to study its effects...

...John E. Money This review covers some modern concepts in the development of drugs to treat appetite disorders. Specific attention is paid to the peripheral satiety system and the role of gastrointestinal peptides such as cholecystokinin in the pathogenesis of satiety. Alterations in neuropeptide Y...

...Reinhard Pietrowsky; Lars Claassen; Hauke Frercks; Horst L. Fehm; Jan Born The gut and brain peptide cholecystokinin (CCK) exerts a number of central nervous effects. Among them are effects on attention and stimulus processing as revealed by modulations of event-related potentials (ERPs...

... interest. All patients suffered from sleep disturbances. Suicidal thoughts did not occur at all. Inner tension was negatively correlated with the anxiogenic cholecystokinin tetrapeptide (CCK-4) in the cerebrospinal fluid (CSF), while reduced sexual interest was negatively correlated with CSF tryptophan...