... predictive factors associated with long-term outcomes in individuals with bipolar disorder. These outcomes include cognitive function, relapse rate, treatment responses, and functional outcomes. The study employs a multifaceted approach, integrating brain imaging, biochemical analyses of cerebrospinal fluid...

...Elena M.D. Schönthaler; Haleh Aminfar; Nina Dalkner; Frederike T. Fellendorf; Johanna Georgi; Melanie Lenger; Andreas Wedrich; Eva Z. Reininghaus Background: Bipolar disorder (BD) is a psychiatric condition with significant health implications due to its comorbidities, premature mortality...

...Tobias Bellaagh Johansson; Anna Luisa Klahn; Andreas Göteson; Christoph Abé; Carl M. Sellgren; Mikael Landén Introduction: Bipolar disorder has been associated with significant structural brain changes, potentially driven by central nervous system (CNS) inflammation. This study aimed to investigate...

... then, fifteen more years have brought further information about lithium. This paper makes a narrative review of the most important articles published in this period. Summary: The selected key literature of 2010–2024 addressed lithium prophylactic efficacy in bipolar disorder (BD), including pediatric, recurrent...

...Hidayet Ece Arat-Çelik; Aysan Eslami Abriz; Klara Coello; Maj Vinberg; Deniz Ceylan Introduction: Bipolar disorder (BD), a mood disorder with recurrent affective episodes and a strong genetic basis is frequently associated with significant comorbidities, both physical and psychiatric, yet its...

...Cristina Cocco; Barbara Noli; Barbara Manconi; Cristina Contini; Elias Manca; Claudia Pisanu; Anna Meloni; Mirko Manchia; Pasquale Paribello; Caterina Chillotti; Raffaella Ardau; Giovanni Severino; Alessio Squassina Introduction: Discriminating bipolar disorder (BD) from major depressive disorder...

...Magda Malewska-Kasprzak; Agnieszka Permoda; Janusz K. Rybakowski Objective: To verify the purinergic hypothesis of bipolar disorder (BD), we assessed the concentration of various components of the purinergic system in manic and depressed bipolar patients. Methods: Sixty-two patients (19 male and 43...

... into subfields. This study aimed to elucidate the relationship between hippocampal subfield volume and cognitive function in patients with SCZ, bipolar disorder (BP), and major depressive disorder (MDD). Methods: The study included 21 patients with SCZ, 22 with BP, and 21 with MDD and 25 healthy controls (HCs...

... among inpatients with bipolar disorder I during their acute phase of mania. Methods: A total of 72 inpatients (mean age: 33.98 years; 23.6% females) with diagnosed bipolar disorder I and during their acute manic phase were randomly assigned either to the adjuvant levetiracetam (250 mg to a maximum...

...Kaat Hebbrecht; Manuel Morrens; Erik J. Giltay; Alexander L.N. van Nuijs; Bernard Sabbe; Seline van den Ameele Introduction: Chronic low-grade inflammation is suggested to play a pathophysiological role in bipolar disorder (BD) and its related cognitive dysfunctions. Although kynurenine (KYN...

...Dahlia Mukherjee; J. Dylan Weissenkampen; Emily Wasserman; Venkatesh Basappa Krishnamurthy; Caitlin E. Millett; Stephen Conway; Erika F.H. Saunders Introduction: Hypothalamic-pituitary-adrenal (HPA) axis dysregulation may contribute to the symptom burden in bipolar disorder (BD). Further...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Bipolar disorder Major depressive disorder Diffusion tensor imaging White matter White matter hyperintensities...

...Kalliopi Tournikioti; Maria Alevizaki; Ioannis Michopoulos; Aimilia Mantzou; Constantin Soldatos; Athanasios Douzenis; Dimitris Dikeos; Panagiotis Ferentinos Introduction: Bipolar disorder (BD) is associated with impairment in cognitive domains such as verbal memory and executive functions. Very...

... abnormalities in biological first-degree relatives and accruing evidence for motor abnormalities in bipolar disorder. In addition to motor dysfunction, there are also shared symptom domains amongst these populations. Objectives: We explored the associations of (1) current and lifetime psychosis and mood symptom...

... functioning, and its disruption can contribute to many medical conditions. The relationship between gut microbiota and the brain has gained attention in mental health due to the mounting evidence supporting the association of gut bacteria with mood and behavior. Patients with bipolar disorder exhibit...

... depressive disorder Bipolar disorder Response Remission Routine outcome monitoring Patients who are admitted to a psychiatric hospital due to depressive symptoms often suffer from an underlying major depressive disorder (MDD) or bipolar depression (BD). Since depressive episodes are often...

... correlations between group differences in amygdala RSFC and clinical measures. Amygdala Bipolar disorder Borderline personality disorder Corticolimbic functioning Neuroimaging The relationship between borderline personality disorder (BPD) and bipolar II disorder (BD II) remains...

... disorders and their treatment. [email protected] Bipolar disorder Mania Animal model Mitochondria © 2019 S. Karger AG, Basel 2019 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced...

...Marco Calabrò; Concetta Crisafulli; Marco Di Nicola; Roberto Colombo; Luigi Janiri; Alessandro Serretti Background: Previous evidence suggested the possible association of FK506 binding protein 5 ( FKBP5 ) gene variants in bipolar disorder (BPD). Objective: Given the need of refinement...

... with bipolar disorder (BD), receiving daily probiotic treatment over a time period of 3 months. Twenty-seven individuals with BD took part in the present study (mean age = 50.7 years, SD = 12.2; females 40.7%). In sum, there was a high compliance rate with 81.5% of the study participants completing all 3 study...