...), but had no effect on renal pathology. These data suggest that amlodipine reduces renal inflammation and abolished glomerular hyperfiltration, but increases blood pressure and exacerbates albuminuria in the rat model of normotensive diabetic kidney disease. We conclude that amlodipine may have limited...

...Sawako Kato; Bengt Lindholm; Peter Stenvinkel; Tomas J. Ekström; Karin Luttropp; Yukio Yuzawa; Yoshinari Yasuda; Yoshinari Tsuruta; Shoichi Maruyama Background/Aims: Inflammation is an established mortality risk factor in chronic kidney disease (CKD) patients. Although a previous report showed...

... participant-blinded. Methods: We performed a prospective, randomized, and patient-blinded cross-over study. Twenty patients on chronic HD received either HD for 2 months followed by post-dilution HDF for 2 months or in opposite order. A range of clinical parameters, as well as markers of inflammation...

...Debasish Banerjee; Allan J. Collins; Charles A. Herzog Background/Aim: The effect of hypertension on mortality in haemodialysis patients is controversial and can be confounded by non-traditional risk factors like systemic inflammation. This study examined the effect of systolic blood pressure (SBP...