...Akiko Owaki; Daijo Inaguma; Akihito Tanaka; Hibiki Shinjo; Shinichiro Inaba; Kei Kurata Background/Aim: High serum alkaline phosphatase (ALP) levels predict mortality independent of bone metabolism parameters and liver function test results in patients on hemodialysis. The relationship between...

...Kiyonori Ito; Susumu Ookawara; Yuichiro Ueda; Haruhisa Miyazawa; Masaya Kofuji; Hideyuki Hayasaka; Takayuki Uchida; Katsunori Yanai; Hiroki Ishii; Mitsutoshi Shindo; Taisuke Kitano; Keiji Hirai; Yoshio Kaku; Taro Hoshino; Kaoru Tabei; Yoshiyuki Morishita Background: Hemodialysis (HD) patients...

.... Hemodialysis Fertility Chronic kidney disease Infertility of women with end stage renal disease (ESRD) has been extensively investigated, but reproductive function in men with ESRD is less well characterized, and few data are available in either men or women with earlier stages of chronic kidney...

...Emilie Trinh; Catherine Weber Background: Fluid overload in patients on conventional hemodialysis is a frequent complication, associated with increased cardiovascular morbidity and mortality. The dialysate sodium prescription is a potential modifiable risk factor. Our primary objective...

... cardiothoracic ratio (CTR) is indicative of a cardiac disorder. However, few reports have revealed an association between the CTR and mortality in patients starting hemodialysis (HD). Methods: Patients with HD initiation (n = 387; mean age, 66.7 ± 12.7 years) were divided into the following three groups...

... rate between fistulas cannulated using buttonhole versus stepladder techniques for patients treated with short daily (SDH) or nocturnal hemodialysis at home (NHD). We also compared patients receiving conventional intermittent hemodialysis (CIHD) using stepladder cannulation. Methods: Data were...

... of hypertension control in hemodialysis patients. Methods: Volume overload was calculated as the difference between total body water (TBW) measured by bioimpedance and TBW estimated by the Watson formula in chronic stable hemodialysis patients. Inadequate control of blood pressure (BP) was defined as the mean...

... the inferior vena cava (IVC) to assess the volemic status in hemodialysis patients. We investigated whether a nephrologist with limited ultrasound training can accurately assess the IVC in patients undergoing hemodialysis. Methods: A cardiologist and a nephrologist consecutively measured the indexed IVC...

...Kazuya Takasawa; Naohisa Tomosugi; Chikako Takaeda; Teiryo Maeda; Norishi Ueda Background/Aims: We examined whether regulation of hepcidin-25 by short- or long-acting recombinant human erythropoietin (rhEPO) is dependent on ferritin and predicts the response to rhEPO in hemodialysis (HD) patients...

...Vasishta S. Tatapudi; Noam Spinowitz; David S. Goldfarb Central venous stenosis is a well-described sequel to the placement of hemodialysis catheters in the central venous system. The presence of an ipsilateral arteriovenous fistula or graft often leads to severe venous dilatation, arm edema...

...Yasuo Kudoh; Shinya Aoyama; Takaaki Torii; Qijie Chen; Daigo Nagahara; Hiromi Sakata; Akihiko Nozawa Background: It is well known that the physical activity in chronic hemodialysis patients decreases compared to that in normal subjects. In order to investigate the effects of L -carnitine...

.... Although inflammatory status is associated with mortality in hemodialysis (HD) patients, it remains to be determined as to whether these composite scores are useful in predicting clinical outcomes. Methods: We calculated the 6 prognostic scores [Glasgow prognostic score (GPS), modified GPS (mGPS...

... the presence of high levels of glycoxidation and lipid peroxidation products in association with atherosclerosis in patients with end-stage kidney disease. Acetates are commonly used buffer for correcting metabolic acidosis in hemodialysis (HD) patients. Since the toxic effects of acetates are well established...

... and cardiovascular mortality in hemodialysis patients. Methods: Baseline skin AF was measured in 105 patients on hemodialysis, 23 had DM. Survival status was assessed after a mean follow-up period of 4.9 years (interquartile range 2.3–6.9 years). Results: Multivariate Cox regression analysis showed skin AF (hazard...

... insulin requirements and several pleiotropic factors in type 2 diabetes patients requiring hemodialysis. Methods: The effect of pioglitazone (30 mg) versus placebo was explored in this prospective, randomized, double-blind parallel multicenter phase II study analyzing data from 36 patients with type 2...

...Akihiko Kato; Takako Takita; Mitsuyoshi Furuhashi; Taiki Fujimoto; Hiroo Suzuki; Yukitaka Maruyama; Yukitoshi Sakao; Hiroaki Miyajima Anti-hepatitis C virus (HCV) antibody seropositivity is independently associated with poor prognosis in hemodialysis (HD) patients. However, anti-HCV antibody cannot...

...Bergur V. Stefánsson; Mats Abramson; Ulf Nilsson; Börje Haraldsson Background/Aims: Data from studies comparing the effect of hemodiafiltration (HDF) and conventional hemodialysis (HD) on clinically important outcomes are insufficient to support superiority of HDF. None of these studies has been...

... that reducing the target Hb would prevent levels >12 g/dl and lead to significant cost savings. Methods: Our target Hb range was reduced to 9–11 g/dl from 10–12 g/dl. Thirty-five chronic hemodialysis (HD) patients received erythropoietin (EPO) and intravenous iron from January to December 2009. Data analysis...

...Bergur V. Stefánsson; Börje Haraldsson; Ulf Nilsson Background/Aims: At our hemodialysis (HD) unit, we noted a drop in the treatment dose of erythropoietin-stimulating agents (ESAs) when the frequency of dose adjustment was reduced from weekly, where doses were withheld if hemoglobin was >130 g...

...Mohamed A. Alabd; Walid El-Hammady; Ahmed Shawky; Wail Nammas; Mohamed El-Tayeb Aims: We sought to explore the response of the corrected QT (QTc) interval duration and QT dispersion (QTD) to hemodialysis. Methods: We enrolled 50 patients with end-stage renal disease undergoing regular hemodialysis...