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Keywords: Valproic acid
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Journal Articles
Neuroimmune Alterations in Autism: A Translational Analysis Focusing on the Animal Model of Autism Induced by Prenatal Exposure to Valproic Acid
Available to PurchaseIohanna Deckmann, Gustavo Brum Schwingel, Mellanie Fontes-Dutra, Victorio Bambini-Junior, Carmem Gottfried
Journal:
Neuroimmunomodulation
Neuroimmunomodulation (2019) 25 (5-6): 285–299.
Published Online: 29 August 2018
... and environmental factors. Valproic acid (VPA) is an anticonvulsant and mood stabilizer that, when used during the gestational period, increases the risk of ASD in the offspring. The animal model of autism induced by prenatal exposure to VPA demonstrates important structural and behavioral features that can...
Journal Articles
Reduced CD4 T Lymphocytes in Lymph Nodes of the Mouse Model of Autism Induced by Valproic Acid
Available to PurchaseDiego Baronio, Guilherme Bauer-Negrini, Kamila Castro, Gustavo Della-Flora Nunes, Rudimar Riesgo, Daniella Arêas Mendes-da-Cruz, Wilson Savino, Carmem Gottfried, Victorio Bambini-Junior
Journal:
Neuroimmunomodulation
Neuroimmunomodulation (2019) 25 (5-6): 280–284.
Published Online: 17 August 2018
...), we aimed to evaluate possible alterations of T cell pools in the lymphoid organs of an animal model of autism induced by valproic acid (VPA). Pregnant Swiss mice received a single intraperitoneal injection of 600 mg/kg of VPA (VPA group) or saline (control group) on day 11 of gestation. Male...
