..., instructions or products referred to in the content or advertisements. Astrocytes Glutamate Cell viability Neurotrophic factors Tumor necrosis factor-α Original Paper Neuroimmunomodulation 2019;26:33 42 DOI: 10.1159/000495211 Received: October 2, 2018 Accepted after revision: November 8, 2018...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2018 Chagas disease Immuno-metabolism Cortisol Tumor necrosis factor-α Interleukin-6 Adipocytokines Tumor necrosis factor-α receptor type-1 ObR Adiponectin receptor...

... and cortisol alone or in combination for 24 h before stimulation with T-dependent (phytohemagglutinin, PHA) and independent activators (lipopolysaccharide, LPS) to study their immunomodulatory role in interleukin-12 (IL-12), tumor necrosis factor-α (TNF-α), interferon-γ (IFN-γ), and IL-10 production in a whole...

... studied in intact and ovariectomized mice. Endotoxemia was mimicked by intraperitoneal administration of bacterial lipopolysaccharide (LPS; 25 mg per mouse) to sham-operated and 21-day ovariectomized mice. Circulating corticosterone, tumor necrosis factor-α (TNFα) and leptin concentrations were monitored...

..., and may represent a natural adaptation of the HPA axis in inflammatory states. A controlled therapeutic trial is necessary to demonstrate whether supplemental glucocorticoids could be beneficial in SS. Tumor necrosis factor-α Interleukin-1β Interleukin-6 Trypanosoma brucei Hypothalamic-pituitary...

.... When 1 µg mIL-1Β was injected a profound hypothermia lasting more than 3 h was observed. Mouse IL-6 (1 µg) failed to alter core temperature after either intravenous (i.v.) or i.p. administration. Human IL-6 was also ineffective. Recombinant mouse tumor necrosis factor-Α (mTNFΑ) also failed to alter...

..., respectively). Conclusion: These data suggest that exhaustive exercise-induced suppression of the plasma TNF-α concentration despite LPS stimulation might depend on translation of TNF-α in tissues. Immune suppression Tumor necrosis factor-α TNF receptors Lipopolysaccharide Toll-like receptor 4 14...

...Cristiane L.R. De La Hoz; Fabiano R. Castro; Leonilda M.B. Santos; Francesco Langone Background: Inducible nitric oxide synthase (iNOS) and tumor necrosis factor-α (TNF-α) are pleiotropic molecules with widespread action in autoimmune diseases. Objective: This study characterizes the distribution...

.... Interferon-γ Interleukin-1β Macrophages Neurodegeneration Nitric oxide Paraneoplastic neurodegeneration T-cell lymphoma Tumor necrosis factor-α ...

... numbers were determined in bronchoalveolar lavage (BAL) fluid. Leukocytes from mediastinal lymph nodes were analyzed by flow cytometry to determine the percentages of T cells producing interleukin-4, interferon-γ and tumor necrosis factor-α. Results: In BAL fluids of stressed or SP-treated animals...

...Shawn Hayley; Owen Kelly; Hymie Anisman Systemic administration of the proinflammatory cytokine, tumor necrosis factor-α (TNF-α), has acute as well as sensitizing effects on behavioral and neurochemical functioning. Objectives: As many of the central consequences of TNF-α are mediated by its p55...

... tissue-destructive morbidity. Exposure to gp120 results in tumor necrosis factor-α (TNF) upregulation, particularly in cells of monocyte lineage. The resultant increased TNF in the microenvironment of the TNF-producing monocyte lineage cells results in increased occupancy of TNF receptors on nearby...

... lipopolysaccharide Pituitary Prolactin Tumor necrosis factor-α ...

...-· Neuroimmunomodulation 2000;8:59 69 69 Lipopolysaccharides Interleukin-6 Tumor necrosis factor-α Brain Rat ...

... the effect of interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) on release of γ-aminobutyric acid (GABA) from mediobasal hypothalamic (MBH) explants and posterior pituitaries (PP) of male rats. IL-6 (10 ng/ml) did not modify basal GABA release from MBH and PP, but significantly increased GABA release...

...Tetsuya Ando; Adrian J. Dunn Endotoxin (LPS) administration has been shown to activate the hypothalamo-pituitary-adrenocortical (HPA) axis and increase cerebral catecholamine and indolamine metabolism and tryptophan concentrations. LPS stimulates the secretion of tumor necrosis factor-α (TNF-α...

...–1 ng/ml. The addition of 1 ng/ml LPS increased the IL-6 release 12-fold to a maximum value of 1,134 ± 85.5 pg IL-6/NL/24 h (mean ± SEM, n = 6). No trace of interleukin-1β (IL-1β) (<3 pg/NL/24 h) or tumor necrosis factor-α (<10 pg/NL/24 h) was detected after LPS stimulation. We examined...

... superoxide and peroxide, and in increased secretion of inflammatory cytokines like interleukin-1β and tumor necrosis factor-α. These cytokines, besides activating neutrophils, B lymphocytes, and T lymphocytes, act on the central nervous system to induce physiological responses like fever and sleep...

...Isao Nagano; Toshihiro Takao; Wakako Nanamiya; Taka Takemura; Mitsuru Nishiyama; Koichi Asaba; Shinya Makino; Errol B. De Souza; Kozo Hashimoto The role of endogenous interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) in modulating the hypothalamic-pituitary-adrenal (HPA) axis response...

... in tissue content of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) following fixed-pressure (40 mm Hg) hemorrhage as well as on the associated activation of the opiate and glucocorticoid systems. Conscious unrestrained nonheparinized male Sprague-Dawley rats were randomized to receive either 6...