...Alexander M. Kuhn; Kelly E. Bosis; Eric S. Wohleb Background: From the original studies investigating the effects of adrenal gland secretion to modern high-throughput multidimensional analyses, stress research has been a topic of scientific interest spanning just over a century. Summary...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 Cancer Cause Epidemiology Mechanism Stress Some authors have argued that using our point of view...

... and anxiety. The mechanisms underlying stress-induced affective dysregulation are likely distinct from those induced by diabetes. A direct comparison between stress- and hyperglycemia-induced affective dysregulation could provide insight into distinct mechanistic targets for depression/anxiety associated...

...Susana Silberstein; Ana Clara Liberman; Paula Ayelén dos Santos Claro; Maria Belén Ugo; Jan M. Deussing; Eduardo Arzt Depression and other psychiatric stress-related disorders are leading causes of disability worldwide. Up to date, treatments of mood disorders have limited success, most likely due...

...Sara Hasanli; Sarah Hojjati; Maryam Koushkie Jahromi Background/Aims: Research evidence regarding immune system responses and adaptations to psychological or physical stresses is controversial. This study aimed to investigate the effect of 8-week psychological stress and exercise activity (chronic...

...Hong Luo; Jing Wei; Yousef Yasin; Si Jia Wu; Andrew Barszczyk; Zhong-Ping Feng; Kang Lee Background: Stress is a prevalent health problem in modern society. If experienced for long periods of time it can lead to immune dysfunctions. Thus, public health management practices must include...

...Chang Yul Kim; Yeon Gyeong Kim; So Jung Sin; Hyojin Koo; Kicheol Cheon; Dongsoo Kim Objectives: Ginsenoside Rg1 and mebicar have been reported to have broad efficacy spectrum, including anti-anxiety and anti-stress. These drugs have been used not only for treatment but also for the purpose...

...Luis Miguel Saavedra; Bertha Fenton Navarro; Luz Torner Objective: Early life stress (ELS) increases the vulnerability to developing psychopathological disorders in adulthood that are accompanied by brain inflammatory processes. However, it is not known how a combined double hit (stress and immune...

...Dongsoo Kim; Chang Yul Kim; Hyojin Koo; Yong Heo; Kicheol Cheon Objective: Predator stress, social defeat stress, and fear conditioning animal models have been applied to investigate combat-related posttraumatic stress disorder (PTSD). However, no animal model psychopharmacological studies have...

... in the conspecifics as a consequence of stress-induced activation of the sympathetic nervous system (SNS) with catecholamine release. In the current study, the nonspecific β-AR blocker d,l -propranolol and the specific β 2 -AR blocker ICI-118.551 were employed as pharmacological tools to assess the extent to which...

...Mary Urbina; Rubén Arroyo; Lucimey Lima Objectives: Serotonin (5-HT) 7 receptors in lymphocytes play a relevant role as modulators of T cell functions and might be modified by stress protocols. The aims of this work were to evaluate: (i) the presence of 5-HT 7 receptors in specific lymphocyte...

...Matilde Medina-Martel; Mary Urbina; Fili Fazzino; Lucimey Lima Objectives: Glucocorticoids and stress cause transcriptional and functional changes on the serotonin transporter (SERT) in the central nervous system. Stress can produce specific modifications of SERT in lymphocytes, which could...

...Pini Matzner; Ofir Hazut; Reut Naim; Lee Shaashua; Liat Sorski; Ben Levi; Avi Sadeh; Ilan Wald; Yair Bar-Haim; Shamgar Ben-Eliyahu Objective: Young adults often encounter sleep deprivation and stressful events. Both have been separately reported to modulate immunity, and occasionally they occur...

...Kristina E. Rehm; Okan U. Elci; Kathryn Hahn; Gailen D. Marshall,Jr. Objective: Marathon training is both physically and psychologically stressful, both of which can lead to altered immunity. The purpose of this study was to determine if the overall immunoregulatory changes associated...

...Charles A. Griffis; Elizabeth Crabb Breen; Peggy Compton; Alyssa Goldberg; Tuff Witarama; Jenny Kotlerman; Michael R. Irwin Background: Proinflammatory pathways may be activated under conditions of painful stress, which is hypothesized to worsen the experience of pain and place medically vulnerable...

... increased in March, May and August while IFN-γ levels were increased in March and May while TGF-β levels showed a significant decrease in March and May. Serum IgA levels were significantly increased during the entire period of the stressful expedition. Therefore, the present study suggests that serum IgA...

...Hyung-Ran Kim; Sohyeon Moon; Hyeon Kook Lee; Jihee Lee Kang; Seikwan Oh; Ju-Young Seoh Objective: Chronic stress is closely related to immune dysfunction. Immune parameters have been analyzed in many ways in humans and animals under chronic stress. Recently, it has been proved that FoxP3...

...Khalid Z. Matalka; Dalia A. Ali Estradiol, progesterone, prolactin and cortisol concentrations are substantially increased during pregnancy. Also, cortisol and prolactin levels are elevated during stress. In the present study, we exposed peripheral blood to estradiol, progesterone, prolactin...

...Marcela Laukova; Peter Vargovic; Lucia Csaderova; Lucia Chovanova; Miroslav Vlcek; Richard Imrich; Olga Krizanova; Richard Kvetnansky Objectives: Stress-induced rise in circulating catecholamines (CAs), followed by modulation of β-adrenergic receptors (adrenoceptors, ARs), is one of the pathways...

...Bilge Pehlivanoglu; Sibel Bayrak; Esin Ileri Gurel; Zeynep Dicle Balkanci Background/Aims: We aimed to explore the immunological outcomes of short-term mental stress in apoptosis in peripheral lymphocytes and variations by gender and hormonal status of the individuals together with possible...