... male Balb/c mice. At the end of this stress period, nitric oxide (NO) production by peritoneal adherent cells and the serum concentration of corticosterone were measured. Moreover, the viability of peritoneal adherent cells and spleen lymphocytes was evaluated by MTT assay. The terminal...

...Malik Hasarmeh; Anna Itzik; Joseph Weidenfeld; Haim Ovadia Objectives: The role of nitric oxide (NO) in modulating the blood-brain barrier (BBB) is not entirely clear. We examined the effect of different NO synthase (NOS) inhibitors and NO donors on the permeability of the BBB in animals...

... that inflammation contributes to the pathogenesis of AD. All- trans -retinoic acid (ATRA) is a bioactive derivative of vitamin A that has shown immunomodulatory effects in many immune disorders. Objectives: In our study, we aimed to investigate in vitro immunomodulatory effects of ATRA on inducible nitric oxide...

... of nitric oxide-mediated pathways. 4 10 2012 6 02 2013 24 5 2013 © 2013 S. Karger AG, Basel 2013 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any...

... biomarkers such as eosinophil peroxidase (EPO), myeloperoxidase (MPO), and nitric oxide (NO) were analyzed in serum, brain, lung, and heart tissue. Protein levels, LDH, and CPK activities were also determined in serum 24 h after injection. Results: In this study, KTX injection induced severe alterations...

... J, Carnio EC: Central but not systemic inhibition of inducible nitric oxide synthase modulates oxytocin release during endotoxemic shock. Peptides 2010;31:706–711. 13. Villa P, Sartor G, Angelini M, Sironi M, Conni M, Gnocchi P, Isetta AM, Grau G, Buurman W, van Tits LJ, et al: Pattern...

... and bone loss were increased in periodontitis and stress groups, and there was also less weight gain. The inflammatory parameters such as prostaglandin E 2 (radioimmunoassay), nitric oxide (radioconversion of 14 C-arginine), tumor necrosis factor (TNF)-α (ELISA) and interleukin (IL)-1β (Western blot...

... elucidated. Nitric oxide (NO) is a known mediator that regulates the release of these hormones. The endocannabinoid system is a new intercellular system that modulates several neuroendocrine actions. Endocannabinoids (eCB) are released as retrograde messengers by many neurons, including hypothalamic...

... that augmented production of nitric oxide (NO) and prostaglandins (PG) is involved in ER, and that inhibitors of their synthesis could prevent ER. Also, we observed an increase in the oxidative damage, evidenced by nitration of tyrosine proteins, due to the peroxynitrite anion. Since an association between...

... neuronal disorders. Systemic control of the intracellular forms of the parasite greatly depends on the establishment of a TH1 response and subsequent nitric oxide (NO) release. At the CNS, it is known that low concentrations of NO promote neuronal survival and growth, while high concentrations exert toxic...

.... Methods: In the present study, we measured the mRNA (real-time RT-PCR) and protein (Western blot) expression of inducible nitric oxide synthase (iNOS) and the release of nitric oxide (NO; Griess reagent) of rat oligodendroglial progenitor cell line OLN-93 after pro-inflammatory stimulation, and searched...

... isoform of nitric oxide synthase by calcium calmodulin kinase II and occurred prior to the appearance of detectable levels of cytokines in NOD glands. VIP acting on NOD macrophages treated with lipopolysaccharide promoted anti-inflammatory effects by inhibiting nitric oxide synthase induction as well...

...J. Tichauer; K. Saud; R. von Bernhardi The strong inflammatory response observed in neurodegenerative diseases can depend on the impairment of the endogenous control of microglial activation, triggering the release of potentially detrimental factors such as cytokines, nitric oxide...

...Alessandro S. Farias; Cristiane de la Hoz; Fabiano R. Castro; Elaine C. Oliveira; Jose R. Ribeiro dos Reis; João S. Silva; Francesco Langone; Leonilda M.B. Santos The involvement of inducible nitric oxide synthase (iNOS), which plays various roles in the progression of autoimmune diseases...

..., the study presents investigations to show the role of nitric oxide and proinflammatory cytokines IL-1, TNF, interferon-γ and alkaline phosphatase in the manifestation of paraneoplastic neurodegeneration. Conclusions: Growth of a T-cell lymphoma is associated with the manifestation of neurodegeneration...

... Nitric oxide Proliferation Epinephrine Norepinephrine © 2005 S. Karger AG, Basel 2005 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic...

...María Ribeiro; Maximiliano Cella; Mariana Farina; Ana Franchi Background/Objective: The aim of our study was first to investigate if there exists an interaction between nitric oxide (NO) and prostaglandin (PG) generation in the estrogenized rat uterus challenged by lipopolysaccharide (LPS...

...Diego Ogando; Maximiliano Cella; María Laura Ribeiro; Carina Weissmann; Julieta Aisemberg; Ana Franchi Objectives: Recent reports point to a role for the nitric oxide/nitric oxide synthase (NO/NOS) system in implantation. It has been suggested that inducible NOS expressed at peri-implantation would...

... transmitter nitric oxide (NO) in mediating LPS-induced sickness behaviour in rats. Treatment with the non-selective NO synthase (NOS) inhibitor N G -nitro- L -arginine ( L -NA) (20 mg/kg; i.p.) increased the severity of LPS-induced sickness behaviour in rats, suggesting that endogenous NO does not act...

...´ micas y bCa´ tedra de Patolog´ a, Servicio de Anatom´ a Patolo´ gica Hospital Misericordia, Facultad de Ciencias Médicas, Universidad Nacional de Co´ rdoba, Argentina Key Words Fungus infections W Candida albicans W Macrophages W Neutrophils W Nitric oxide W H2O2 W Neuroimmunology W Chronic varied...