... not been fully appreciated until the late 1900s, when a growing interest in how cytokines in the cerebrospinal fluid (CSF) might be relevant in chronic pain conditions emerged. Since then, the field has evolved, and nowadays neuroinflammation is considered to be involved in the pathophysiology of chronic...

...: Galectin-3 activates the NLRP3/pyroptosis signaling pathway to promote microglial activation and neuroinflammation during epilepsy disease progression. [email protected] 2 02 2023 23 10 2023 3 11 2023 © 2023 The Author(s). Published by S. Karger AG, Basel Open Access...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 Streptozotocin Hyperglycemia Stress Depression Anxiety Neuroinflammation Diabetes mellitus (DM...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 IL-33/ST2 pathway Central nervous system Ischemic stroke Neuroinflammation Soluble ST2 Regulatory T cells...

..., and motor or cognitive disabilities. The neuroinflammation plays an important role in the neurological damage; therefore, reducing it could provide neuroprotection. The leuprolide acetate (LA) has shown to have neuroregenerative and immunomodulator properties in other nervous system injuries. Objective...

... phenotype of cerebral endothelial cells in response to both SARS-CoV-2 and immune cells invasion (immunothrombosis) are the major drivers of neurodamage. Calcitriol and hydroxyderivatives of lumisterol and tachisterol could play an adjuvant role in neuroprotection through mitigation of neuroinflammation...

...Yongxiang Yang; Yuqin Ye; Kexia Fan; Jianing Luo; Yongjian Yang; Yuan Ma Introduction: Neuroinflammation contributes to secondary injury after traumatic brain injury (TBI), which has been mainly mediated by the microglia. MiR-124 was reported to play an important role in the polarization...

... studies indicate the absence of the virus in the brain of many COVID-19 patients who developed neurological disorders. Thus, the COVID-19 mechanisms for stimulating cognitive dysfunction may include neuroinflammation, which is mediated by a sustained systemic inflammation, a disrupted brain barrier...

... Neuroinflammation VEGF Multiple sclerosis (MS) is a chronic autoimmune inflammatory disease characterized by neural demyelination and axonal degeneration in the central nervous system (CNS) [1]. The main etiology of MS is yet unknown; however, studies showed environmental and genetic factors and infections...

..., instructions or products referred to in the content or advertisements. 2022 Superficial dorsal horn Gabapentin Pregabalin Cytokines Neuroinflammation Gabapentinoids, such as gabapentin and pregabalin, are drugs to treat symptoms of neuropathic pain [ 1 ]. Initially, they were established...

...Lin Zhu; Ce Dong; Xiongfei Yue; Pengzhen Ge; Guozhen Zheng; Zhanying Ye; Baogen Pan Background: Neuroinflammation subsequent to traumatic brain injury (TBI) is important for the recovery of patients and is associated with neurodegenerative changes post-TBI. The tripartite motif containing 44...

... from any ideas, methods, instructions or products referred to in the content or advertisements. Catalpol Isoflurane Hippocampus Cognition Neuroinflammation Inhalation anesthesia has been widely used in clinical practice; however, mounting research works have revealed the close...

...Yong-Ping Zhang; Yu-Yu Li; Cai Zhang; Ya-Jun Li; Bai-Ping Liu; Yan Zhang; Ju-Da Lin; Cai Song Background: Activated microglia can trigger pro-inflammatory cytokine releases and neuroinflammation, which may inhibit astrocytes to produce neurotrophins and anti-inflammatory factors. Both eventually...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Adrenal hormones Cytokines Hypothalamus Neuroinflammation Sepsis...

... advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Neuroinflammation Neuroprotection Anti...

... of general anesthetic exposure on the neurodevelopment of offspring. H19 miR-17-5p Isoflurane Neurotoxicity Neuroinflammation © 2021 S. Karger AG, Basel 2021 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other...

... neurological damage and infarct area and promoting cognitive function. Conclusion: This study provided protective roles of ZGP on cell viability and apoptosis induced by OGD/R. In addition, ZGP played protective roles on neuroinflammation and cognitive function in rats. [email protected] 18 06...

.... After the treatment of NGR1, the elevated levels of IL-6, TNF-α, and IL-1β induced by isoflurane were all decreased significantly in the hippocampal tissues of rats. Additionally, the repressive action of NGR1 in neurological impairment and neuroinflammation was eliminated by downregulating miR-29a...

... immune responses (CD4 + CD25 + FoxP3 + , B regulatory cells). Dysfunctional regulatory immune cells might contribute to systemic and neuroinflammation observed in mood disorders via different mechanisms, such as: (i) failure to develop adequate stress-related responses, (ii) indirectly through microglial...

... nitrogen species (RNS). The serum methylmalonic acid, cytokines, ROS, and RNS were across the blood-brain barrier and induced cognitive impairment. The small molecule substances such as serum NO, MDA, and GSH participated in the process of neuroinflammation and oxidative stress injury induced by MMA...