... the abundance of five proteins (cochlin, NPTXR, reelin, Sez6l, and VPS13C) and decreasing the abundance of two proteins (CPQ, IGFBP-7) in the CSF. Simultaneously, LGG increased the expression of Il10 mRNA, encoding the anti-inflammatory cytokine interleukin 10, in the hippocampus. Conclusion: Oral LGG altered...

... necrosis factor α Interleukin 10 Lipopolysaccharide Our body is able to defeat and overcome infections and injuries thanks to the ability of the immune system to activate humoral and cell-mediated responses starting with the development of an inflammatory response [ 1 ]. An impaired immune...

... the safety of high-dose vitamin D in MS. Objective: This study compared the effects of high-dose vitamin D on interleukin 10 (IL-10) levels in MS patients in a double-blind, randomized clinical trial. Methods: Ninety-four patients with relapsing remitting MS (RRMS) were randomized into a treatment...

..., or the induction of IL-6. These results indicate that LPS-induced IL-10 can act as an important endogenous inhibitor of brain TNF production and suggest an anti-inflammatory role for IL-10 in the central nervous system. Endotoxin Interleukin 1 Interleukin 10 Hypothalamus-pituitary-adrenal axis Serum amyloid...