... individuals with a low-grade systemic inflammation. Methods: We collected the axillary body odour of individuals with severe seasonal allergy ( N = 14) and healthy controls ( N = 10) during and outside the allergy season and measured serum levels of two inflammatory cytokines (tumour necrosis factor-α...

...Harald Engler; Alexandra Brinkhoff; Benjamin Wilde; Andreas Kribben; Hana Rohn; Oliver Witzke; Manfred Schedlowski; Sven Benson Introduction: Experimental endotoxemia is a translational model of systemic inflammation that has contributed significantly to our current understanding of sickness...

...Sven Benson; Bianka Karshikoff The immune system and the central nervous system exchange information continuously. This communication is a prerequisite for adaptive responses to physiological and psychological stressors. While the implicate relationship between inflammation and pain is increasingly...

... neural reflex inhibition of inflammation. We will discuss the contribution of the adrenal glands to the reflex control of inflammation, noting that the neurally mediated release of catecholamines in the systemic circulation is responsible for the enhancement of the anti-inflammatory cytokine interleukin...

... behaviors, cognitive declines, inflammation, and oxidative stress in the hippocampus of asthmatic rats. Methods: Rats were allocated to five groups: control, asthma, asthma/vehicle, asthma/myrtenol, and asthma/budesonide. Asthma was elicited in the rats by ovalbumin, and the animals were then exposed...

... effect on inflammation. However, the therapeutic effects and underlying pharmacological mechanisms of Nodakenetin for inflammatory pain remain unclear. Methods: Intraplanar injection of complete Freund’s adjuvant (CFA) was used to establish a model of chronic inflammation pain in C57BL/6 mice...

...Natalia Färber; Jorge Manuel; Marcus May; Nilufar Foadi; Florian Beissner Introduction: Inflammation is a mechanism of the immune system that is part of the reaction to pathogens or injury. The central nervous system closely regulates inflammation via neuroendocrine or direct neuroimmune mechanisms...

...-α) generation and Iba-1, COX-2, and iNOS expressions, whereas silencing SNHG1 did the opposite. miR-181b functions as a downstream miRNA of SNHG1. In LPS-treated cells, the inhibition of miR-181b induced by SNHG1 promoted inflammation response and the expressions of Iba-1, COX-2, and iNOS...

...Moisés E. Bauer; Antônio L. Teixeira Mood disorders are associated with chronic low-grade systemic (sterile) inflammation, with increased plasma levels of pro-inflammatory mediators targeting all tissues including the brain. Importantly , pro-inflammatory cytokines (ex., tumor-necrosis factor alpha...

... concentration of IL-1β, IL-6, and TNF-α induced by STZ. STZ might repress the mRNA levels of ERβ, and ZGW management weakened the declined mRNA expression of ERβ. ZGW might play a protective role in AD rats against the injury of STZ on cognition and neuro-inflammation by improving the mRNA expression of ERβ...

... to inhibit oxidative stress and inflammation compared to the TBI group. Conclusion: Collectively, our study is first to demonstrate the protective effect of RMZ against experimentally induced TBI in rats. yang_dale@163.com 30 03 2021 25 04 2021 15 7 2021 © 2021 S. Karger AG...

... of inflammasomes [ 16 ]. However, whether PKM2 is involved in I/R-induced nerve injury or inflammation is unclear. TLRs are critical regulators in immune and inflammatory responses [ 17 ]. Meanwhile, TLR4 is responsible for inflammatory response and involved in diseases of the central nervous system...

...) of the reference gene transcript [ 23 ]. PCR efficiencies were calculated, according to E = 10[−1/slope]. 21 04 2020 12 11 2020 3 3 2021 Alp ha7 nicotinic acetylcholine receptor BV2 cell cultures Inflammation Microglia Inflammation in the nervous tissue...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. COVID-19 SARS-CoV-2 Inflammation Immunity Cytokine The emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) from Wuhan, China, that causes...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Depression Inflammation Lipopolysaccharide Cytokines Glucocorticoids LPS induced depressive-like behavior...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2019 Negative regulation TNFAIP3 TNIP Innate immunity Major depressive disorder Inflammation Antidepressants Major depression is a disorder that affects daily...

... and epilepsy. Micro-RNA-155 (miR-155) plays a critical role in immunity and -inflammation. This study aims to explore the function of miR-155 and miR-155-mediated inflammation in epilepsy. Methods: About 8-week-old male C57BL/6 mice were administered an intraperitoneal injection (i.p.) of kainic acid (KA) (15...

...Jingjing Liu; Xin Xiong; Yutong Sui Objectives: Inflammation and apoptosis play a critical role in the pathological progress of traumatic brain injury (TBI). Isoliquiritigenin is a bioactive component extracted from licorice roots, which possesses anti-inflammatory and anti-apoptotic properties...

... soccer players Premenstrual syndrome Inflammation Mood states Stress hormones Premenstrual syndrome (PMS) is a functional and recurrent syndrome characterized by physical symptoms and psychological disturbances [ 1 ]. The prevalence of PMS ranges from 8 to 86%, with differences in intensity...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Zika virus Neuroimmunomodulation Inflammation Autism In early 2015, a Zika virus (ZIKV) outbreak was identified in the northeastern...