... to in the content or advertisements. 2024 Phylogeny Fitness Trade-off Cytokine Inflammation Sickness Disease Why does the psychoneuro-endocrine-immune network, which evolved to protect the individual against disease, sometimes cause disease and even death [ 1‒6 ]? This is a classical question...

..., instructions or products referred to in the content or advertisements. 2024 Neuroimmunomodulation Inflammation Vitamin D Neurodamage Cognition The special issue of Neuroimmunomodulation on “COVID-19, Hormones and Brain” collects five comprehensive reviews on main topics of neuroendocrine...

..., instructions or products referred to in the content or advertisements. 2024 Inflammation Pain Medically unexplained symptoms Cerebral blood oxygen Cerebral blood flow Immune system and central nervous system (CNS) are two selfish organs, which hierarchically control self-allocation of energy...

... individuals with a low-grade systemic inflammation. Methods: We collected the axillary body odour of individuals with severe seasonal allergy ( N = 14) and healthy controls ( N = 10) during and outside the allergy season and measured serum levels of two inflammatory cytokines (tumour necrosis factor-α...

...Sven Benson; Bianka Karshikoff The immune system and the central nervous system exchange information continuously. This communication is a prerequisite for adaptive responses to physiological and psychological stressors. While the implicate relationship between inflammation and pain is increasingly...

...Harald Engler; Alexandra Brinkhoff; Benjamin Wilde; Andreas Kribben; Hana Rohn; Oliver Witzke; Manfred Schedlowski; Sven Benson Introduction: Experimental endotoxemia is a translational model of systemic inflammation that has contributed significantly to our current understanding of sickness...

... neural reflex inhibition of inflammation. We will discuss the contribution of the adrenal glands to the reflex control of inflammation, noting that the neurally mediated release of catecholamines in the systemic circulation is responsible for the enhancement of the anti-inflammatory cytokine interleukin...

... behaviors, cognitive declines, inflammation, and oxidative stress in the hippocampus of asthmatic rats. Methods: Rats were allocated to five groups: control, asthma, asthma/vehicle, asthma/myrtenol, and asthma/budesonide. Asthma was elicited in the rats by ovalbumin, and the animals were then exposed...

... effect on inflammation. However, the therapeutic effects and underlying pharmacological mechanisms of Nodakenetin for inflammatory pain remain unclear. Methods: Intraplanar injection of complete Freund’s adjuvant (CFA) was used to establish a model of chronic inflammation pain in C57BL/6 mice...

...Natalia Färber; Jorge Manuel; Marcus May; Nilufar Foadi; Florian Beissner Introduction: Inflammation is a mechanism of the immune system that is part of the reaction to pathogens or injury. The central nervous system closely regulates inflammation via neuroendocrine or direct neuroimmune mechanisms...

...Moisés E. Bauer; Antônio L. Teixeira Mood disorders are associated with chronic low-grade systemic (sterile) inflammation, with increased plasma levels of pro-inflammatory mediators targeting all tissues including the brain. Importantly , pro-inflammatory cytokines (ex., tumor-necrosis factor alpha...

... concentration of IL-1β, IL-6, and TNF-α induced by STZ. STZ might repress the mRNA levels of ERβ, and ZGW management weakened the declined mRNA expression of ERβ. ZGW might play a protective role in AD rats against the injury of STZ on cognition and neuro-inflammation by improving the mRNA expression of ERβ...

... to inhibit oxidative stress and inflammation compared to the TBI group. Conclusion: Collectively, our study is first to demonstrate the protective effect of RMZ against experimentally induced TBI in rats. yang_dale@163.com 30 03 2021 25 04 2021 15 7 2021 © 2021 S. Karger AG...

..., instructions or products referred to in the content or advertisements. Cerebral ischemia-reperfusion injury Pyruvate Kinase isozymes M2 High-mobility group box 1 TLR4/MyD88/TRAF6 Inflammation Ischemic stroke accounts for 85% of all cases of stroke [ 1, 2 ]. As a common cerebrovascular disease...

... on several inflammatory readouts and showed that α7 nAChR modulators with little or no ion channel activity inhibited this anti-inflammatory mechanism. Alp ha7 nicotinic acetylcholine receptor BV2 cell cultures Inflammation Microglia Inflammation in the nervous tissue or neuroinflammation can...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. COVID-19 SARS-CoV-2 Inflammation Immunity Cytokine The emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) from Wuhan, China, that causes...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Depression Inflammation Lipopolysaccharide Cytokines Glucocorticoids LPS induced depressive-like behavior...

... disorder Inflammation Antidepressants Major depression is a disorder that affects daily quality of life [ 1, 2 ] and presents the leading cause of disability affecting nearly 350 million people worldwide. Major depressive disorder (MDD) is a risk factor for physical illness and morbidity [ 3‒5...

... and epilepsy. Micro-RNA-155 (miR-155) plays a critical role in immunity and -inflammation. This study aims to explore the function of miR-155 and miR-155-mediated inflammation in epilepsy. Methods: About 8-week-old male C57BL/6 mice were administered an intraperitoneal injection (i.p.) of kainic acid (KA) (15...

...Jingjing Liu; Xin Xiong; Yutong Sui Objectives: Inflammation and apoptosis play a critical role in the pathological progress of traumatic brain injury (TBI). Isoliquiritigenin is a bioactive component extracted from licorice roots, which possesses anti-inflammatory and anti-apoptotic properties...