...Maria Serpente; Rossana Bonsi; Elio Scarpini; Daniela Galimberti Immune activation and inflammation, likely triggered by amyloid-beta (Aβ) deposition, play a remarkable role in the pathogenesis of Alzheimer's disease (AD), which is the most frequent cause of dementia in the elderly. The principal...

... the olfactory tract delays the acute-phase response (APR) and the APR is attenuated by immunization. Objectives: To determine if immunization affects OB localization of influenza or the molecular brain mechanisms regulating APR. Methods: Male mice were immunized with PR8 influenza, then OB viral RNA, APR...

... interaction between autonomic innervation and the immune system. Using a muscarinic antagonist, [ 3 H]quinuclidinyl benzilate ([ 3 H]QNB), we revealed different characteristics of m-AchR expression in lymphocytes isolated from the spleen, peripheral blood or thymus of Wistar rats. To further explore...

...Hidekazu Fujimaki; Yoshika Kurokawa; Masaki Kakeyama; Naoki Kunugita; Yukiko Fueta; Takaichi Fukuda; Hajime Hori; Keiichi Arashidani Objective: The effects of low-level formaldehyde (FA) inhalation on the amount of nerve growth factor (NGF) in the hippocampus of immunized mice were studied. Methods...