... the effects of ELS on the immune system have changed since the first studies on this topic were published. Key Messages: Across different study designs, species, and methods, a consistent association between childhood adversity and a pro-inflammatory phenotype has been reported. We critically discuss which...

...Rebecca Sohn; Zsuzsa Jenei-Lanzl The sympathetic nervous system (SNS) is a major regulatory mediator connecting the brain and the immune system that influences accordingly inflammatory processes within the entire body. In the periphery, the SNS exerts its effects mainly via its neurotransmitters...

...Sara Hasanli; Sarah Hojjati; Maryam Koushkie Jahromi Background/Aims: Research evidence regarding immune system responses and adaptations to psychological or physical stresses is controversial. This study aimed to investigate the effect of 8-week psychological stress and exercise activity (chronic...

...Josemar Marchezan; Eduardo Geyer Arrussul Winkler dos Santos; Iohanna Deckmann; Rudimar dos Santos Riesgo Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with an unknown etiology and currently few effective therapies. Immune system alterations have being demonstrated in ASD...

..., whereas no effects on maternal aggressive behavior were found. On LD5, a reduction of the frequency of USVs was observed in pups, but no signs of inflammation were found. At weaning, an increase in immune system activity was observed, but no differences in open-field behavior were found. Conclusion...

..., instructions or products referred to in the content or advertisements. Parkinson’s disease Inflammation Immune system Cognition Depression Parkinson's disease (PD) is the second most common neurodegenerative disorder worldwide. The prevalence of PD is generally estimated to hover around 0.3...

... cellular elements of the brain innate immune system likely to be involved in such processes are microglia. In an attempt to search for new disease-modifying drugs, the immune system has been addressed, with the aim of removing deposition of Aβ or tau by developing vaccines and humanized monoclonal...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Ehrlich ascitic tumor Sleep restriction Immune system Paradoxical sleep While the prevalence of sleep disorders...

... of natural killer cells was detected in women, whereas it was decreased in men. After stress induction, serum NO levels remained the same in women and increased in men. Although a correlation was not found between immune system changes and NO levels, glucocorticoids seem to have a role in the observed...

...Jacqueline Mays; Cherié L. Butts Crosstalk exists between the nervous, endocrine, and immune systems, and perturbations in these interactions have been associated with disease. This includes production of neuroendocrine factors that alter immune system activity and increase susceptibility...

... only. Responses were attenuated in women compared to men. Our data provide insights into the temporal interactions between the endocrine and immune systems in response to acute heavy resistance exercise in men and women. © 2011 S. Karger AG, Basel 2011 Copyright / Drug Dosage / Disclaimer...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Cytokines Experimental autoimmune encephalomyelitis Immune system Multiple sclerosis Sertraline Original Paper Neuroimmunomodulation 2011;18:117 122 DOI: 10.1159...

... axis Hippocampus Immune system ...

... plays during axonal degeneration and regeneration has not been fully established. Understanding the molecular basis of these interactions between the immune system and peripheral nerve injury would open the possibility of targeting these inflammatory mediators as therapeutic interventions...

...I. Camacho-Arroyo; L. López-Griego; J. Morales-Montor Cytokines are highly inducible, secretory proteins that mediate intercellular communication in the immune system. They are grouped in several protein families, namely tumor necrosis factors, interleukins, interferons and colony-stimulating...

...Javier Romeo; Julia Wärnberg; Sonia Gómez-Martínez; Ligia Esperanza Díaz; Ascensión Marcos Stress has long been suspected to play a role in the etiology of many diseases and may be detrimental to health. Nowadays, the communication between the neuroendocrine and the immune systems is well...

...Adele Barnard; Daniel Layton; Melanie Hince; Samy Sakkal; Claude Bernard; Ann Chidgey; Richard Boyd The nervous, endocrine, and immune systems interact to adapt to infection, inflammation, and tissue injury. Neural control is mediated in several ways, one of them being through the neuroendocrine...

...Liu Hui; Hou Diandong; Zhao Baoxia; Wu Da; Yin Hong; Wu Xiaoyi We set out to use proteomic profiling as a means of defining serum peptides that are indicative of a stress response related to an impact on the immune system. Two types of mouse models with the immune response impaired under stress...

... (CNS) modulates immune function by signaling target cells of the immune system through autonomic and neuroendocrine pathways. Neurotransmitters and hormones produced and released by these pathways interact with immune cells to alter immune functions, including cytokine production. Cytokines produced...

...-tolerance Immune system Physical exercise Abstract Backgorund/Aims: Modulations in the immune function by stress are a well-known phenomenon. Acute restraint stress may induce impaired T-lymphocyte responses. Moderate physical training is associated with beneficial effects on immunological functions. We...