... in the thymus since lymphoblasts express phenotypic markers comparable to those described in thymocytes in distinct stages of development. Although around 50% of T-ALL patients present a thymic mass, T-ALL is characterized by peripheral blood and bone marrow involvement, and central nervous system (CNS...

... has been linked to several inflammatory disorders. In human and rodents, the broad expression of IL-33 in spinal cord tissues and brain indicates its central nervous system-specific functions. Growing evidence supports the protective effects of the IL-33/ST2 pathway in ischemic stroke, along...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Glutamic acid decarboxylase Antibody Myelitis Central nervous system Neoplasm Glutamic acid decarboxylase (GAD...

... injection with IL-6 leads to sprouting in the subcortical visual connections and suggest that small changes in IL-6 levels might be sufficient to impair the correct neuronal circuitry fine-tuning during brain development. Interleukin-6 Central nervous system Retinotectal projections Plasticity...

... = 0.0001) but not of treatment (p > 0.05). The prefrontal cortex presented higher BDNF levels than other structures (ANOVA/Student-Newman-Keuls test, p = 0.0001). Considering the relationship between BDNF levels in all three structures, we found an effect of central nervous system structures (p = 0.01...

... = 0.005] or hrNMO + NMO (OR = 6.350, p = 0.028). Conclusion: H. pylori infection was present in most Chinese patients with NMO and hrNMO, and may be a risk factor for the NMO spectrum. Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS) thought...

..., and b Department of Neurology, The First Affiliated Hospital of GuangDong Pharmaceutical University, Guangzhou, PR China Key Words Neuromyelitis optica Multiple sclerosis Aquaporin Central nervous system Abstract Background: Serum neuromyelitis optica immunoglobulin G (NMO-IgG) is used...

...André Luis Bombeiro; Maria Regina D’Império Lima; Gerson Chadi; José Maria Álvarez Background/Aim: Chagas’ disease is caused by Trypanosoma cruzi and occurs in most Latin American countries. The protozoan may colonize the central nervous system (CNS) of immune-compromised human hosts, thus causing...

... factors. In recent years, evidence has elucidated that some of these proteins as well as their receptors are also produced in the central nervous system (CNS) by specific neural cell lineages under physiological and pathological conditions. Cytokines regulate a variety of processes in the CNS, including...

... Key Words Adhesion molecules Transcription factor Central nervous system MUC18 MCAM CD146 Mader Egr-1 OOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO Abstract The proteins MUC18 and Mader have been identified as markers of tumor progression...

...Iain L. Campbell; Anna K. Stalder; Yvette Akwa; Axel Pagenstecher; Valérie C. Asensio To better understand the actions of cytokines in the mammalian central nervous system (CNS), we have developed transgenic mice in which the expression of various cytokines including interleukin (IL)-3, IL-6, IL-12...

..., instructions or products referred to in the content or advertisements. Interleukin-1 receptor accessory protein Central nervous system Lipopolysaccharides RT-PCR ...

..., instructions or products referred to in the content or advertisements. Tumor necrosis factor-α Hyperalgesia Prostaglandin Interleukin-1 Pain Central nervous system Rat ...

...Paul E. Gottschall; Suman Deb In neurodegenerative disease or after brain injury, parenchymal cells in the central nervous system are activated to produce inflammatory mediators, mainly consisting of cytokine-induced factors, in a manner similar to, but clearly different from a peripheral...

..., instructions or products referred to in the content or advertisements. Interleukin Tumor necrosis factor-α Central nervous system Transport Brain Endothelium Saturable Mouse Human ...