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Keywords: Transforming growth factor-β
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Journal Articles
Subject Area:
Nephrology
Nephron Physiology (2006) 103 (3): p139–p148.
Published Online: 22 June 2006
.... Epithelial-mesenchymal transition Tubulointerstitial fibrosis Transforming growth factor-β Gremlin Diabetic nephropathy Bone morphogenic proteins Characteristic features of renal fibrosis include an atrophied tubular architecture and an accumulating extracellular matrix (ECM) that relentlessly...
Journal Articles
Subject Area:
Nephrology
Nephron Physiology (2005) 101 (4): p82–p91.
Published Online: 14 November 2005
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Hypertension Nitric oxide Interstitial fibrosis Simvastatin Renal inflammation p21 Monocyte chemoattractant protein-1 Transforming growth factor-β Several...
Journal Articles
Subject Area:
Nephrology
Nephron Physiology (2003) 95 (4): p83–p91.
Published Online: 30 December 2003
... to declining renal function. Tranilast (N-[3,4-dimethoxycinnamoyl]anthranilic acid), an inhibitor of transforming growth factor-β (TGF-β), used to treat hypertrophic scars has recently been shown in pilot studies to exert a beneficial effect in advanced diabetic nephropathy in humans. However, its effects...
Journal Articles
Subject Area:
Nephrology
Nephron Physiology (2003) 94 (2): p28–p38.
Published Online: 04 July 2003
... deposition disease produce increased extracellular matrix (ECM) when compared with HMCs not exposed to fibrogenic LCs. This overproduction of ECM proteins is regulated by transforming growth factor-β (TGF-β); blocking TGF-β normalizes the production of ECM proteins. All ECM proteins, after synthesis, have...
Journal Articles
Subject Area:
Nephrology
Nephron Physiology (2003) 93 (1): p14–p20.
Published Online: 30 October 2002
... of sodium citrate therapy on kidney cortex levels of transforming growth factor-β (TGF-β), and the response to calcium citrate ingestion. Rats were provided with citrate salts in their food, and renal clearance, blood pressure, blood chemistry, and survival determinations were made. Sodium citrate therapy...