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Keywords: Platelet-derived growth factor
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Journal Articles

Platelet-Derived Growth Factor Reorganizes the Actin Cytoskeleton through 3-Phosphoinositide-Dependent and 3-Phosphoinositide-Independent Mechanisms in Human Mesangial Cells

Subject Area:
Nephrology
Lisa Harper, Yasuyo Kashiwagi, Charles D. Pusey, Bruce M. Hendry, Jan Domin
Journal: Nephron Physiology
Nephron Physiology (2007) 107 (2): p45–p56.
https://doi.org/10.1159/000107805
Published Online: 05 September 2007
...Lisa Harper; Yasuyo Kashiwagi; Charles D. Pusey; Bruce M. Hendry; Jan Domin Background: Platelet-derived growth factor (PDGF) is a potent activator of mesangial cell proliferation and migration. Although phosphoinositide 3-kinase (PI3K) enzymes are important downstream targets of the PDGF receptor...
View article titled, <span class="search-highlight">Platelet</span>-<span class="search-highlight">Derived</span> <span class="search-highlight">Growth</span> <span class="search-highlight">Factor</span> Reorganizes the Actin Cytoskeleton through 3-Phosphoinositide-Dependent and 3-Phosphoinositide-Independent Mechanisms in Human Mesangial Cells
Open the PDF for <span class="search-highlight">Platelet</span>-<span class="search-highlight">Derived</span> <span class="search-highlight">Growth</span> <span class="search-highlight">Factor</span> Reorganizes the Actin Cytoskeleton through 3-Phosphoinositide-Dependent and 3-Phosphoinositide-Independent Mechanisms in Human Mesangial Cells in another window
Journal Articles

Macrophage Infiltration and Cellular Proliferation in the Non-Ischemic Kidney and Heart following Prolonged Unilateral Renal Ischemia

Subject Area:
Nephrology
Hirobumi Tokuyama, Darren J. Kelly, Yuan Zhang, Renae M. Gow, Richard E. Gilbert
Journal: Nephron Physiology
Nephron Physiology (2007) 106 (3): p54–p62.
https://doi.org/10.1159/000103910
Published Online: 15 June 2007
... the AT1 antagonist losartan (30 mg/kg/day). After 24 h of renal ischemia, changes in the contralateral kidney and heart were examined. Results: Contralateral non-ischemic kidneys displayed increased expression of platelet-derived growth factor-B (PDGF-B) in association with increased tubular cell...
View article titled, Macrophage Infiltration and Cellular Proliferation in the Non-Ischemic Kidney and Heart following Prolonged Unilateral Renal Ischemia
Open the PDF for Macrophage Infiltration and Cellular Proliferation in the Non-Ischemic Kidney and Heart following Prolonged Unilateral Renal Ischemia in another window