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Keywords: Osteopontin
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Journal Articles
Subject Area:
Nephrology
Nephron Physiology (2007) 106 (3): p54–p62.
Published Online: 15 June 2007
... proliferation. Gene expression for the macrophage chemokine osteopontin (OPN) was similarly increased along with substantial macrophage infiltration. In the heart, expression of OPN and macrophage numbers were increased. All of these changes, in both the heart and kidney were attenuated by losartan. Conclusion...
Journal Articles
Subject Area:
Nephrology
Nephron Physiology (2004) 98 (2): p43–p47.
Published Online: 19 October 2004
...Jack G. Kleinman; Jeffrey A. Wesson; Jeremy Hughes Osteopontin (OPN) is a phosphorylated protein of wide tissue distribution that is found in association with dystrophic calcification including in the organic matrix of kidney stones. It is a strong inhibitor of crystal formation and growth in vitro...
Journal Articles
Subject Area:
Nephrology
Nephron Physiology (2003) 93 (3): p76–p86.
Published Online: 31 March 2003
...Ki-Hwan Han; Ju-Young Jung; Jung-Ho Cha; Hyang Kim; Kirsten M. Madsen; Jin Kim Osteopontin (OPN) is a secreted phosphoprotein expressed constitutively in the descending thin limb (DTL) and papillary surface epithelium (PSE) of the kidney. Although its function is not fully established, a role...