... lithium clearance 1.9-fold and fractional lithium excretion 2.8-fold. Fractional water and sodium excretion from distal nephron segments was not significantly affected by Ap 4 A. Conclusion: These results suggest that Ap 4 A induces natriuresis mainly through inhibition of proximal tubular reabsorption...

... and on natriuresis and phosphaturia in 3/4 nephrectomized (3/4nx) and Sham rats. Methods: The 3/4nx and Sham rats were placed in metabolic cages and received the MAO-A-selective inhibitor Ro-411049 (7.5 mg·kg –1 bid) and/or the COMT-selective inhibitor BIA 3-202 (30 mg·kg –1 bid) orally for 3 days during high sodium...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Endothelin Endothelin-converting enzyme Salt balance Natriuresis Renal medulla Rats, high/low salt intake...

...) [ 3, 4 ]. Expressing natriuresis as FENa has the advantage to narrow the SD patients to a more homogeneous group with FENa lower than 0.5% in 100% of these patients [ 3, 4 ]. However, in a series [ 4 ]much larger than that we described earlier [ 3 ], we recently assessed that only 60% of SIADH...

... and natriuresis were unchanged. In ERPF– naloxone did not affect WI-induced MAP, ERPF, RVR and BRS changes, while it blunted sodium excretion. Our data provide the first evidence of a differentiate renal hemodynamic response to WI in hypertension; they also suggest that while OS may significantly potentiate...