...Ihab M. Mahmoud; Abd El-Aziz M. Hussein; Mohammed E. Sarhan; Ali A. Awad; Ibrahim El Desoky Background: L-Arginine (L-arg) and Prostaglandin E 1 (PGE 1 ) have been used effectively as single agents to ameliorate renal ischemia-reperfusion injury. We hypothesized that combined treatment with L-arg...

... Otuska rat models as age-matched controls. Either L-arginine (a NO precursor) or L-NAME (a nitric oxide synthase inhibitor) was administered from the age of 22 weeks. Clinical parameters and serum and urinary NO 2 +NO 3 levels were measured, in addition to renal histological findings and ED-1-positive...

... transport [ 3, 4 ]. Supplementation of L -arginine ( L -Arg), the substrate of NO synthesis (NOS), has proven to be beneficial for the acute phase of renal failure [ 5 ] and for kidney function in terms of glomerular filtration rate (GFR) and renal plasma flow (RPF) in various forms of ARF [ 6, 7 ], e.g...

... perfused rat kidney, and the effect of amino acid L -arginine (in the drinking water, 2.25 g/l) on renal dysfunction induced by gentamicin. When gentamicin-treated groups were compared with the control group, it was observed that BUN and creatinine levels increased significantly. Also, the relaxant...