... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Diabetes Diabetic nephropathy Glomerular hyperfiltration Tubuloglomerular feedback Salt paradox Adenosine A 1 receptor Proximal tubule...

..., 3 = moderate fluorescence, 4 = intense fluorescence, as previously published [ 18, 25 ]. Thirty glomeruli per section were counted by two observers who were unaware of the study group from which the section was derived. Diabetic nephropathy Hypertension Nephrin Albuminuria Spontaneously...

...Hiroshi Kamijo; Makoto Higuchi; Kazuhiko Hora Background: Nitric oxide (NO) is known to play a role in diabetic nephropathy, but the molecular basis for this effect remains unclear. Method: Otsuka Long-Evans Tokushima Fatty spontaneous diabetic rat models were used along with Long-Evans Tokushima...

... of the cysteine knot protein superfamily is critical to the process of nephrogenesis but quiescent in normal adult kidney. There is increasing evidence that gremlin expression reactivates in diabetic nephropathy, and in the diseased fibrotic kidney per se. Known to antagonize members of the bone morphogenic...

... the administration of streptozotocin (STZ) to Wistar rats induces a diabetic state that is not accompanied by hypertension [ 16 ], its use in spontaneously hypertensive rats (SHR) can produce an animal model more closely related to human diabetic nephropathy, where hyperglycemia and mesangial stretch would act...

...C. Henningsen; G. Zahner; F. Thaiss Background: Diabetic nephropathy, which is characterized by renal hypertrophy and accumulation of extracellular matrix, is one of the leading causes for end-stage renal disease. Pathophysiological changes, which finally lead to the development of diabetic...