...María F. Albertoni Borghese; Mónica P. Majowicz; María C. Ortiz; María del Rosario Passalacqua; Norma B. Sterin Speziale; Norberto A. Vidal Background/Aims: Diabetes mellitus may impact on the regulation of renal Na + -glucose cotransporter type 2 (SGLT2), however, previous studies have yielded...

...Volker Vallon; Jana Schroth; Joseph Satriano; Roland C. Blantz; Scott C. Thomson; Timo Rieg Background: In early type 1 diabetes mellitus, changes in proximal reabsorption influence glomerular filtration rate (GFR) through tubuloglomerular feedback (TGF). Due to TGF, a primary increase in proximal...

... the GLUT2 gene expression changes in the kidney of diabetic rats, by using insulin or phlorizin treatment. Methods: Rats were rendered diabetic and studied 20 days later: 4–12 h after one single injection of insulin or phlorizin, and 1–6 days after insulin or phlorizin injection twice a day, comparing...

...Tomoyo Kagawa; Genzou Takemura; Ken-ichiro Kosai; Ichijiro Murata; Takamasa Ohno; Tomoyuki Takahashi; Masayasu Esaki; Rumi Maruyama; Takako Fujiwara; Hiroshige Ohashi; Hisayoshi Fujiwara Background: Effect of hepatocyte growth factor (HGF) has scarcely been determined on diabetic nephropathy...

...Jelena Klisic; Vera Nief; Livia Reyes; Patrice M. Ambühl Background: Early stages of diabetic nephropathy are characterized by alterations of glomerular filtration, increased tubular sodium and water reabsorption, and systemic volume expansion, which may be a major cause for the development...