... for the manifestation of increased salt intake. Effects of aldosterone on both the brain and kidney synergize with the effects of angiotensin II. Thus, mineralocorticoids appear to induce similar molecular pathways in the kidney, brain, and possibly tongue, which could provide opportunities for more effective...

...Marcelo R. Choi; Brenda M. Lee; Cecilia Medici; Alicia H. Correa; Belisario E. Fernández Background/Aims: Dopamine (DA) uptake inhibition in the renal cortex, elicited by angiotensin II (ANG II), is mediated by AT 1 receptors and signals through the phospholipase C pathway and activation of protein...

...Marcelo R. Choi; Cecilia Medici; Mariela M. Gironacci; Alicia H. Correa; Belisario E. Fernández Background/Aims: Angiotensin II (ANG II) decreases dopamine (DA) uptake in renal cortex activating AT 1 receptors. We investigated the signaling pathways that mediate this action and the incidence of DA...

... with the development and progression of albuminuria. Components of the diabetic milieu (high glucose, accumulation of glycated proteins, high intrarenal angiotensin II (ANG II), and hypertension-induced mechanical stress) result in activation of cytokine systems, the most important of which are transforming growth...

...Marcelo R. Choi; Alicia H. Correa; Vanesa del Valle Turco; Fernando Aprile Garcia; Belisario E. Fernández Background/Aims: Angiotensin II (ANG II) and dopamine (DA) are both important regulators of sodium and water transport across renal proximal tubules. Previous studies demonstrate that atrial...

...Christine Maric; Wei Zheng; Thomas Walther Background/Aims: Neutral endopeptidase (NEP) inhibition attenuates renal damage in the diabetic kidney, but little is known about the mechanisms of this renoprotective effect. Methods: We examined the interaction between angiotensin II (Ang II) and atrial...

... regulation Glucocorticoids Angiotensin II Na + -K + (NH 4 + )-2Cl – cotransporter Gene expression mRNA stability Ammonium ion NH 4 + urinary excretion is one of the main components by which the kidney regulates systemic acid-base balance. Indeed, NH 4 + represents two third and ∼90...

..., instructions or products referred to in the content or advertisements. Renal failure, hypertension control Hypertension Angiotensin-converting enzyme inhibitors AT-1 receptor antagonism Angiotensin II Sodium diets Original Paper Nephron Physiol 2005;101:p14 p20 DOI: 10.1159/000086037 Received...

... + -ATPase on microdissected CCD, OMCD and IMCD segments. The effect of angiotensin II AT 1 receptor inhibition and protein recovery (24% protein) on H + -ATPase activity was studied. Methods: Bafilomycin-sensitive H + -ATPase activity on CCD, OMCD and IMCD segments of LP (protein 8%) and control rats CP...

...Nobukazu Ishizaka; Kan Saito; Eisei Noiri; Masataka Sata; Ichiro Mori; Minoru Ohno; Ryozo Nagai Background: Angiotensin II infusion into rats causes iron deposition in the kidney, which may augment the pro-proteinuric effects of this octapeptide. We have investigated whether administration of iron...

... and evaluated the effects of CDH on the noradrenaline (NA) and angiotensin II (AngII) induced increases in blood pressure and reductions in RBF. Continuous intravenous administration of CDH at 0.25 µg/kg/min did not affect the mean arterial pressure (MAP), but increased heart rate and RBF. Continuous...

...Steven P. Clavant; Josephine M. Forbes; Vicki Thallas; Tanya M. Osicka; George Jerums; Wayne D. Comper Angiotensin II (ANG II) is intimately involved in normal renal function, and is estimated to exist at a normal physiological range of 6–10 n M within the renal tubules. The potential role...