...Carsten A. Wagner Aldosterone is classically associated with the regulation of salt and potassium homeostasis but has also profound effects on acid-base balance. During acidosis, circulating aldosterone levels are increased and the hormone acts in concert with angiotensin II and other factors...

.... Therefore, aldosterone participates in the phenotypical transformation of VSMCs. In preclinical models, aldosterone antagonism reduces vascular osteoinduction. Patients with CKD suffer from hyperphosphatemia predisposing to vascular osteogenic transformation, potentially further fostered by concomitant...

... involvement in depression, the focus was mostly on cortisol/corticosterone, whereas aldosterone appears to be the ‘forgotten' stress hormone. Part of the reason for this is that the receptors for aldosterone, the mineralocorticoid receptors (MR), were thought to be occupied by glucocorticoids in most parts...

... the pathophysiology in conditions like salt-sensitive hypertension and chronic heart failure. Here we review the central role of the mineralocorticoid aldosterone in both the increase in renal salt reabsorption and sodium appetite. We discuss the working hypothesis that aldosterone activates similar signaling...

...Thomas B. Jensen; Trairak Pisitkun; Jason D. Hoffert; Uffe B. Jensen; Robert A. Fenton; Helle A. Praetorius; Mark A. Knepper; Jeppe Praetorius Background/Aims: Aldosterone exerts multiple long-term effects on the distal renal tubules. The aim of this study was to establish a method for identifying...

..., instructions or products referred to in the content or advertisements. Aldosterone Mineralocorticoid Glucocorticoid Oestrogen Rapid responses Steroid Renal function is subject to precise regulation by the action of steroid hormones that in turn affects whole body electrolyte balance...

... in dehydrated infants. In such infants, the risk of hyperkalemia is probably low. Na + ,K + -ATPase K + -ATPase Potassium Hyperkalemia Metabolic acidosis Fluid therapy Electrolyte disorders Dehydration Aldosterone 14 04 2005 27 11 2005 14 7 2006 © 2006 S. Karger AG, Basel...

... of parathormone (PTH), it may also be exerted through regulation of profibrotic factors such as aldosterone. In adrenal cortex cell cultures, PTH increases aldosterone release. The objective of this work is to assess the effect of parathyroidectomy on aldosterone levels and on cardiac fibrosis and apoptosis...

...Farouk Markos; Vincent Healy; Brian J. Harvey Background: In this study, the mechanism of the rapid non-genomic effect of aldosterone on Na + /H + exchanger (NHE)-mediated intracellular pH (pH i ) recovery from an acid load in murine M-1 cortical collecting duct cells was assessed. Methods...

...Dierk H. Endemann; Konrad Wolf; Carsten A. Boeger; Günter A.J. Riegger; Bernhard K. Krämer Background: Aldosterone seems to play a role in the development of chronic renal failure and proteinuria. We investigated the adrenal aldosterone production and the adrenal renin-angiotensin system (RAS...

...Anette Fiebeler; Hermann Haller The mineralocorticoid receptor mediates the effects of aldosterone. In addition to its influence on fluid and electrolyte, aldosterone plays a role in cardiac hypertrophy, tissue fibrosis, and modulation of vascular reactivity. However, the intracellular signaling...