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Keywords: Zymography
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Journal Articles
Subject Area:
Women's and Children's Health
Journal:
Neonatology
Biology of the Neonate (2006) 90 (3): 185–196.
Published Online: 22 September 2006
... by pursing immunoblotting and immunohistochemistry and zymography/reverse zymography to assess the alterations in activities of MMPs and their inhibitors. Results: We observed significant down-regulation of MMP-9 activity in hypoplastic lungs at the later fetal developmental stages, whereas MMP-2 activity...
Journal Articles
Subject Area:
Women's and Children's Health
Thomas L. Miller, Suzanne M. Touch, Clifford J. Singhaus, Polani B. Ramesh Babu, Aaron Chidekel, Thomas H. Shaffer
Journal:
Neonatology
Biology of the Neonate (2006) 89 (4): 236–243.
Published Online: 14 June 2006
... zymography for the activity of MMPs, and reverse zymography for TIMPs. Immunostainings on neonatal lamb tracheal rings were used to localize MMP-2 and 9. Results: Analysis revealed an age-dependent decrease in total MMP-2 quantity and the ratio of active to latent forms. TIMP-2 shows a time-dependent...