... independent clone was identified in each library that produced protein that bound these monoclonal antibodies. The protein encoded by the cDNA in each clone bound radiolabeled recombinant surfactant protein-A. It is concluded that human and porcine alveolar cell SP-A binding proteins have been identified...

...Bengt Robertson; Tore Curstedt; Egbert Herting; Bo Sun; Toyoaki Akino; Klaus P. Schäfer We measured alveolar-to-vascular leakage of surfactant protein A (SP-A) in immature newborn rabbits delivered at a gestational age of 27 days. Experimental animals received, via a tracheal cannula, 2 ml/kg...

... gene. An example of the latter is cystic fibrosis (CF) where the disease-causing gene has been clearly identified as the CF transmembrane conductance regulator gene, but genetic variants of the mannose binding protein and surfactant protein A have been associated with disease severity in CF...

...Arie B. Vaandrager; Lambert M.G. van Golde The lung surfactant proteins (SP) A and D are large multimeric proteins and belong to a family of collagenous C-type lectins designated collectins. Both SP-A and SP-D are believed to play a role in the innate immunity of the lung. SP-A and SP-D bind...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Pulmonary surfactants Collectins Immunity Surfactant protein A Surfactant protein D Review Biol Neonate 2004;85:326 332 DOI: 10.1159...