...Hiroki Kitaoka; Ryota Kobayashi; Kosuke Tanaka; Masahiko Watanabe; Tetsuya Isayama Introduction: Inhaled nitric oxide (iNO) is a selective pulmonary vasodilator. However, its effectiveness in the treatment of bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH) and severe BPD...

..., instructions or products referred to in the content or advertisements. 2024 Congenital diaphragmatic hernia Neonatology Ductus arteriosus Pulmonary hypertension Congenital diaphragmatic hernia (CDH) is a developmental discontinuity of the diaphragm that allows abdominal viscera to herniate...

...Shanmukha Mukthapuram; Addison Donaher; Nara S. Higano; James A. Rowe; Jean A. Tkach; Jason C. Woods; Paul S. Kingma Introduction: Pulmonary hypertension often complicates bronchopulmonary dysplasia (BPD) and infants with BPD plus pulmonary hypertension experience higher mortality rates. Current...

...) partly controls the synthesis of surfactant proteins by type 2 alveolar epithelial cells (AEC2), and germline mutations are known to be associated with brain-lung thyroid syndrome. We report the case of a full-term neonate who developed refractory respiratory failure with pulmonary hypertension requiring...

..., the median OSI was 5.0 (interquartile range 3.1–10.6). Twenty-seven infants developed pulmonary hypertension on a median of day 1 (1-1), of which 15 infants had an indication for ECMO-therapy, and 6 infants died. Maximum OSI values were associated with pulmonary hypertension, ECMO-therapy, and mortality...

... temperature, and preductal versus postductal location of oxygen saturation measurement or arterial blood sampling. The predictive values for pulmonary hypertension, need for extracorporeal membrane oxygenation therapy, and survival at discharge were evaluated. Results: Of 33 subjects included, 398 paired...

...Steven H. Abman Despite growing awareness of the clinical importance of pulmonary hypertension (PH) in preterm infants, uncertainty persists regarding the different clinical settings in which abnormalities of pulmonary vascular growth, function, and structure contribute to high morbidity...

...Dalya Munves Ferguson; Vikas S. Gupta; Pamela A. Lally; Matias Luco; KuoJen Tsao; Kevin P. Lally; Neil Patel; Matthew T. Harting; for The Congenital Diaphragmatic Hernia Study Group Introduction: Pulmonary hypertension (PH) is the major pathophysiologic consequence of congenital diaphragmatic...

...Catherine M. Avitabile; Sophie Ansems; Yan Wang; Maria V. Fraga; Haresh M. Kirpalani; Huayan Zhang; Laura Mercer-Rosa; Erik A. Jensen Background: Premature infants with severe bronchopulmonary dysplasia (sBPD) are at risk of pulmonary hypertension (PH). Serum brain natriuretic peptide (BNP) is used...

...Anna Claudia Massolo; Anshuman Paria; Lindsey Hunter; Emma Finlay; Carl F. Davis; Neil Patel Background: Congenital diaphragmatic hernia (CDH) is an important cause of mortality and morbidity in the neonatal period. Pulmonary hypertension and pulmonary hypoplasia are key pathological findings...

...Katrin Mehler; Floris E. Udink Ten Cate; Titus Keller; Ursula Bangen; Angela Kribs; André Oberthuer Background: Pulmonary hypertension (PH) affects 1 in 6 infants with a birthweight <1,000 g (extremely low birthweight; ELBW) and is frequently associated with bronchopulmonary dysplasia (BPD...

... ventilatory support, and have clinical evidence of pulmonary hypertension. Little information exists on the prevalence of and risk factors associated with pulmonary hypertension in this cohort of infants. Objectives: To describe the prevalence of and risk factors associated with pulmonary hypertension among...

...Hye Won Kwon; Han-Suk Kim; Hyo Soon An; Bo Sang Kwon; Gi Beom Kim; Seung Han Shin; Ee-Kyung Kim; Eun Jung Bae; Chung Il Noh; Jung-Hwan Choi Background: The long-term cardiovascular outcomes of pulmonary hypertension (PH) in preterm infants with bronchopulmonary dysplasia (BPD) are uncertain...

...Angela M. Montgomery; Alia Bazzy-Asaad; Jeremy D. Asnes; Matthew J. Bizzarro; Richard A. Ehrenkranz; Constance G. Weismann Background: Pulmonary hypertension (PH) in infants with bronchopulmonary dysplasia (BPD) is associated with increased morbidity and mortality. Elevated levels of N-terminal pro...

... of hypoxic respiratory failure (HRF) and persistent pulmonary hypertension of the newborn (PPHN). An indwelling arterial line or arterial punctures are necessary to obtain PaO 2 for the calculation of OI. Oxygenation can be continuously and noninvasively assessed using pulse oximetry. The use of the oxygen...

...Neil Patel Background: Pulmonary hypertension and secondary cardiac dysfunction are important contributors of morbidity and mortality in infants with congenital diaphragmatic hernia (CDH). Milrinone, a phosphodiesterase-3 inhibitor, may be useful in this setting for its combined actions...

... critically ill term newborns with acute heart failure and pulmonary hypertension in the absence of any underlying heart malformation and/or previous cardiosurgical procedures. During the neonatal period, levosimendan may represent an ideal drug for immature myocardium characterized by a higher calcium...

... studies and identification of areas for further research. 10 05 2010 24 08 2010 27 10 2010 Congenital diaphragmatic hernia Consensus guidelines Ventilation High-frequency oscillatory ventilation Extracorporeal membrane oxygenation Pulmonary hypertension Hemodynamic management...

...Katarzyna Dabrowska; Dorothy Hehre; John Ladino; Eduardo Bancalari; Cleide Suguihara Background: A single dose of NONOate attenuates pulmonary hypertension (PH) induced by group B Streptococcus (GBS) infusion and this is accompanied by a decrease in systemic vascular resistance (SVR). Objective...

... from any ideas, methods, instructions or products referred to in the content or advertisements. Hypocapnia Pulmonary hyperventilation Extracorporeal membrane oxygenation Lung injury Pulmonary hypertension Original Paper Biol Neonate 1993;64:254-260 W.A.A. Klöpping-Ketelaarsa M. Havenithb...