...James X. Sotiropoulos; Ola D. Saugstad; Ju Lee Oei Background: Oxygen is crucial for life but too little (hypoxia) or too much (hyperoxia) may be fatal or cause lifelong morbidity. Summary: In this review, we discuss the challenges of balancing oxygen control in preterm infants during fetal...

..., and recommendations for screening practices and therapeutic management in preterm infants are missing. Summary: In this review, we outline clinical and experimental evidence of Ureaplasma -driven fetal and neonatal morbidity, critically examining inconsistencies across some of the existing studies. We explore...

... the effect of cerebral oximetry-guided treatment in the first 72 h after birth on mortality and severe brain injury diagnosed by cranial ultrasound in extremely preterm infants (EPIs). This ancillary study evaluated the effect of cerebral oximetry on global brain injury as assessed by magnetic resonance...

...Kirsten Glaser; Erik A. Jensen; Clyde J. Wright Background: The rates of major neonatal morbidities, such as bronchopulmonary dysplasia, necrotizing enterocolitis, preterm white matter disease, and retinopathy of prematurity, remain high among surviving preterm infants. Exposure to inflammatory...

...Taiki Shimotsuma; Seiichi Tomotaki; Mitsuyo Akita; Ryosuke Araki; Hiroko Tomotaki; Kougoro Iwanaga; Akira Kobayashi; Akihiko Saitoh; Yasutaka Fushimi; Junko Takita; Masahiko Kawai Introduction: Bronchopulmonary dysplasia (BPD) is associated with neurodevelopmental outcomes of preterm infants...

...Seiichi Tomotaki; Tetsuya Isayama; Tohru Kobayashi; Satoshi Masutani; Hidenori Kawasaki; Atsushi Nakayama; Toshifumi Ikeda; Katsuaki Toyoshima; the PLASE Study Group Investigators Introduction: A feature of the management of extremely preterm infants in Japan is proactive circulatory management...

... with several respiratory disorders and is a pathophysiological feature of lung disease. We investigated whether elevated urine HA is a biomarker of an unfavorable 40-week respiratory outcome in preterm infants. Methods: Infants comprised a cohort of preterm neonates <31 weeks gestational age (GA) from...

... in the incidence of NEC and culture-positive late-onset sepsis during the COVID-19 pandemic, the number of extremely preterm births was unchanged. COVID-19 pandemic Preterm infant Necrotizing enterocolitis Sepsis Necrotizing enterocolitis (NEC) is one of the dominating causes of morbidity...

...Anna Maria Hibbs; Zhengyi Chen; Nori M. Minich; Richard J. Martin; Thomas M. Raffay; Peter M. MacFarlane; Juliann M. Di Fiore Introduction: Length of hospitalization varies widely in preterm infants and can be affected by multiple maternal and neonatal factors including respiratory instability...

... Bronchopulmonary dysplasia Antenatal antibiotic exposure Preterm infant Despite major developments, including the use of antenatal corticosteroids, surfactant, and new ventilation techniques, the incidence of bronchopulmonary dysplasia (BPD), the chronic lung disease of prematurity, has not decreased...

... Extremely preterm infant Neonatal intensive care Neonate Patent ductus arteriosus Preterm infant The ductus arteriosus is a normal and essential foetal cardiovascular structure while in utero [ 1 ]. It connects the pulmonary artery to the aorta and serves to shunt 90% of the blood from the right...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 Caffeine Preterm infant Intensive care Bronchopulmonary dysplasia Methylxanthines are frequently prescribed medications...

... neurodevelopmental outcomes in very preterm infants (VPIs), but less is known about the long-term effect of meningitis and the combined impact of both meningitis and IVH. Our objective was to examine the long-term neurodevelopmental outcomes of VPIs with late onset sepsis and meningitis, with and without IVH...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 Extremely low birth weight infant Preterm infant Outcome Survival Recent advances in perinatal...

...Abed A. Baiad; Imaan Z. Kherani; Marko M. Popovic; Glen Katsnelson; Rajeev H. Muni; Kamiar Mireskandari; Nasrin N. Tehrani; Tianwei Ellen Zhou; Peter J. Kertes Background: Retinopathy of prematurity (ROP) is the most common cause of preventable blindness in preterm infants. First-line treatments...

...Janina Marissen; Mercedes Gomez de Agüero; Parul Chandorkar; Lilith Reichert; Kirsten Glaser; Christian P. Speer; Christoph Härtel The skin of preterm infants is a delicate organ with critical structural and functional differences as compared to term born infants. Unique features contribute...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 Preterm infant Oxygen saturation target Nasal intermittent positive pressure ventilation Nasal high-frequency...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 Best evidence Dosing recommendations Preterm infant Term infant Many drugs...

...-invasive respiratory support Nutrition Oxygen supplementation Patent ductus arteriosus Preterm infant Respiratory distress syndrome Surfactant therapy Thermoregulation Survival of preterm infants continues to improve, with those at 22–23 weeks of gestation now having reasonable chances...

...Maija Seppä-Moilanen; Sture Andersson; Turkka Kirjavainen Background: The effect of supplemental oxygen on sleep has not been studied in preterm infants. Methods: We studied 18 stable late-preterm infants with observed periodic breathing at a median gestational age of 36 weeks. Polysomnography...