... of edaravone plus therapeutic hypothermia (TH + EV) with those of TH alone after a hypoxic-ischaemic insult in the newborn piglet. Anaesthetized piglets were subjected to 40 min of hypoxia (3–5% inspired oxygen), and cerebral ischaemia was assessed using cerebral blood volume. Body temperature was maintained...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Animal model Piglet Necrotizing enterocolitis Biomarker Stomach Necrotizing enterocolitis (NEC) is the most serious enteral feeding-related gastrointestinal...

...P.A. Flecknell; R. Wootton; P. Royston; M. John The effect of oral feeding on the response to fasting and to an intravenous glucose infusion was investigated in neonatal piglets. Piglets, which had received no food at birth, reduced both their rates of glucose appearance and glucose utilisation...

...Tom Stiris; Thor Willy Ruud Hansen; Jan-Petter Odden; Lars Mørkrid; Dag Bratlid Ocular blood flow was studied in newborn piglets during light exposure and light combined with hyperoxia. Light caused a significant increase in ocular blood flow which returned to values not significantly different...

...P.A. Flecknell; W. Wootton Cerebral blood flow and cerebral metabolism were studied in 8 fasting neonatal piglets. Cerebral blood flow was not significantly different (p > 0.1) at 24 h (75.0 ± 30.7 ml/min/100 g) and 48 h (74.2 ± 32.3 ml/min/100 g) of age. Blood glucose concentration was lower...

...M.J. Dauncey; R. Geers The number of nuclear T 3 receptors in the longissimus dorsi muscle has been determined in normal and runt (intrauterine growth-retarded) newborn piglets. Values of maximal binding capacity (B max ), as calculated by Scatchard analysis, were 48.2 ± 4.3 and 39.7 ± 4.7 mol × 10...

... and protein than the Lw pigs, whereas both breeds had similar levels of body fat and liver and muscle glycogen. Plasma concentrations of fructose and α-fetoprotein were lower (p < 0.05) in the newborn Ms pigs. Cold resistance test performed in a 6–7 °C environment on the same piglets when aged 2 and 24 h...

...Immanuela R. Moss; Lynn M. Sugarman; Debra L. Goode In normoxia, the opioid antagonist naltrexone (3 mg/kg i.v.) increased respiratory drive (dITP/dt), frequency (f) and ventilation (V) and decreased tidal volume (Vt) in 1-to 4-day-old anesthetized piglets; it increased dITP/dt in 10- to 18-day-old...

...B.R. Weström; J. Svendsen; B.G. Ohlsson; C. Tagesson; B.W. Karlsson The intestinal transmission of two macromolecular markers, of similar molecular weight but different susceptibility to proteolytic digestion, was investigated in the neonatal pig. Piglets of varying age (0 h-7 days old) were given...

...Charles Richardson; Arthur J. Miller Variations in intraesophageal pressure (P es ) to 5-min exposures of 100% O 2 , 10%O 2 , and 6% CO 2 were studied in successive days during the first 2 months of 8 piglets. Pressure measurements were integrated over time to obtain mean pressure changes for each...

... fetus is 66.4, 89.2 in the piglet and 168 in the adult pig. TG accounts for 95% of total proteins; its content increases with age. Mean iodine content of TG is 0.70 μg 127 I/100 μg in the fetus, 0.78 in the piglet and 0.97 in the adult pig. The average number of molecules of thyroxine residues is 1.6...

...Harvey L. Leary, jr.; James G. Lecce To elucidate further the role of digesta in the cessation of transport of macromolecules to the blood by enterocytes of neonatal piglet small intestine, a portion of the ileum was surgically isolated and vented to the exterior. The ability of this isolated...

...J.P. Royston; P.A. Flecknell; R. Wootton The statistical distribution of birth weights in 54 litters of piglets was examined in an attempt to identify intra-uterine growth-retarded animals. Although birthweight distribution was normal in some litters, in others there appeared to be a discrete...

...P.A. Flecknell; R. Wootton; Muriel John Cerebral utilization rates of glucose and oxygen were measured in 18 conscious, unrestrained neonatal piglets. Cerebral glucose utilization rate was 26.9 ± 2.8 μmol/min/100g (mean ± SEM), cerebral oxygen utilization rate was 160 ± 10 μmol/min/ 100 g...

...R. Wootton; P.A. Flecknell; Muriel John A technique has been developed for the accurate and precise measurement of cerebral blood flow in the conscious, unrestrained neonatal piglet. Repeat determinations under conditions in which the animals could observe the experimenters showed...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Fetus Piglet Adrenal Liver Weight Ascorbic acid Adrenocortical activity Biol. Neonate 22: 338-347 (1973...

...Lori Petryk; Hope A. Weiler The objective was to determine the effects of dexamethasone (Dex) on growth and arachidonic (AA) and docosahexaenoic (DHA) acid status. Piglets were randomized to suckling or formula feeding plus Dex or placebo treatment for 15 days. Weight and length at the beginning...

...Nerida L. Gallagher; L. Roger Giles; Peter C. Wynn Saliva was collected from neonatal piglets in order to assess the secretory dynamics of cortisol in the newborn piglet. Saliva was collected from two litters of piglets (n = 16) from multiparous sows at 07.00, 11.00, 15.00 and 19.00 h on days 0, 1...

... the van’t Hoff or ‘Q10’ effect) and face-cooling, might synergistically induce hyperthermia. This proved not to be the case. We now report on a ‘febrile’ state adding Salmonella abortus equi pyrogens. The combination of face-cooling and pyrogen administration to 14 already hot piglets produced an increase...

... in neonates. To understand better the interactions of inhaled NO and ET-1, we investigated the effects of ET-1 infusions with and without inhaled NO in two groups of piglets, one group pretreated with L -nitro-arginine methylester ( L -NAME) and the other not pretreated. Inhaled NO (60 ppm) was administered...