... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 Oxygen Preterm infant Resuscitation Oxygen saturation Oxidative stress Oxygen is the only drug on the World Health Organization list of 479 essential medicines that has...

...Carlo Dani; Simone Pratesi; Giuseppe Ranieri; Guido Mannaioni; Elisabetta Gerace Background: We recently demonstrated that oxygen-glucose deprivation (OGD) and unconjugated bilirubin (UCB) can damage mature and immature organotypic hippocampal slices and induce an oxidative stress similar to what...

... problem by improving prevention strategies. While BPD pathogenesis is multifactorial, it is accepted that oxidative stress (OS) contributes to pulmonary inflammation and vascular dysplasia characteristic of its clinical presentation [7]. OS mechanisms may begin in utero, and studies have associated...

... about lipid peroxidation levels and IH in this larger and more common preterm population. Objective: To determine the association between oxidative stress and IH in moderate preterm infants. Method: Oxygen saturation was continuously monitored in 51 moderate preterm infants (i.e., 31 + 0/7 to 33 + 6/7...

...). There was no consistent reduction in inflammation and oxidative stress in piglets ventilated with 21 or 100% oxygen. Objectives: We aimed to investigate hypoxic resuscitation, i.e., PPV with 18% oxygen, in profoundly asphyxiated piglets with cardiac arrest. We hypothesized that resuscitation with 18% oxygen would result...

.... Evidence that free radicals may contribute to pathological processes such as bronchopulmonary dysplasia (BPD), a disease of prematurity associated with increased lung injury, inflammation and oxidative stress, led to trials of the antioxidant vitamin E (α-tocopherol) to prevent BPD with variable results...

.... Oxidative stress due to free radical formation and the initiation of abnormal oxidative reactions appears to play a key role. Docosahexanoic acid (DHA), a main component of brain membrane phospholipids, may act as a neuroprotectant after hypoxia-ischemia by regulating multiple molecular pathways and gene...

...Lianqiang Che; Yue Xuan; Liang Hu; Yan Liu; Qin Xu; Zhengfeng Fang; Yan Lin; Shengyu Xu; De Wu; Keying Zhang; Daiwen Chen Objective: In offspring with intrauterine growth restriction (IUGR), where oxidative stress may play an important role in inducing metabolic syndrome, nutrition restriction has...

.... Oxidative stress Oxygen saturation Pulse oximetry Antioxidants Biomarkers An adequate balance between pro-oxidant and antioxidant elements is essential for biologic processes. Redox (transmembrane electron potential) regulation depends on control elements, which are functionally organized in redox...

... by hyperglycemia and oxidative stress. Furthermore, oxidative stress may be even present in pregnant women with an adequate metabolic control which could be explained by downregulation of the antioxidant status in diabetic pregnancies [ 11,12 ]. Interestingly, fetuses from gestational diabetic mothers have...

... of the ketone bodies acetoacetate (AA) and β-hydroxybutyrate (BHB). Objective: The aim of this study was to examine how hyperketonemia in diabetic mothers affects markers of inflammation and oxidative stress in their offspring. Methods: Blood was obtained from 23 diabetic mothers and 13 healthy mothers...

... target for these infants postnatally is still unknown. 1 6 2012 In the present article we discuss some effects of hyperoxia and oxidative stress in the newborn with particular focus on the integrity of DNA and expression of genes. We present some implications of hyperoxia on the cellular...

... relevant interventions in the delivery room (DR). Oxygen needs during resuscitation still represent a conundrum for neonatologists. While hyperoxemia favors oxidative stress and subsequent organ injury, hypoxemia is associated with long-term neurodevelopmental impairment. It has been shown that ELBW...

... and vascular dysfunction. Objectives: We hypothesized that the adverse effects of postnatal glucocorticoid therapy are secondary to oxidative stress and that antioxidant treatment would diminish unwanted effects. Methods: Male rat pups received a clinically relevant course of dexamethasone (Dex), or Dex...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. EGRAC Erythrocytes FAD Free radicals Glutathione reductase Oxidative stress Preterm infants Riboflavin Very low...

..., Italy Key Words. Newborn Erythrocyte Oxidative Stress Abstract. In order to evaluate postnatal red blood cell (RBC) properties and whole-blood rheology, 36 healthy full-term newborn infants were tested twice (cord blood, 4th-day blood) for whole-blood flow rate, hematocrit, hemoglobin (Hb), RBC...

...Serafina Perrone; Mariangela Longini; Barbara Marzocchi; Anna Picardi; Carlo V. Bellieni; Fabrizio Proietti; Antonello Rodriguez; Giovanni Turrisi; Giuseppe Buonocore Background: Oxidative stress (OS) plays a crucial role in pathological conditions during the early neonatal period. The newborns...

...Chun Hay Ko; Raymond Pui-On Wong; Pak Cheung Ng; Karen Li; Kit Man Chui; Patrick Man-Pan Yuen; Tai Fai Fok Background: Recent studies suggest that a low antioxidant level in preterm infants may predispose them to increased oxidative stress and results in hyperbilirubinemia, whereas glucose-6...

...Veniamin Ratner; Siarhei Slinko; Irina Utkina-Sosunova; Anatoly Starkov; Richard A. Polin; Vadim S. Ten Background: Premature infants with lung injury often experience intermittent episodes of hypoxemia. Objective: This study investigates whether intermittent hypoxemia exacerbates oxidative stress...

... Resuscitation Noninvasive ventilation Continuous positive airway pressure Oxidative stress Inflammation formerly Biology of the Neonate Review Neonatology 2009;95:286 298 DOI: 10.1159/000178770 Published online: December 2, 2008 The First Golden Minutes of the Extremely-Low-Gestational-Age Neonate...