...Jan-Petter Odden; Teresa Farstad; Ellen B. Roll; Christian Hall; Dag Bratlid The isotope-labelled microsphere method was used to study blood flow autoregulation in the brainstem (BS), cerebellum (CBL), cerebrum (CBR) and choroid plexus (ChPl) in 21 newborn piglets exposed to hypoxemia...

... cortex of newborn piglets. NNLA was administered intravenously to 22 piglets at doses of 5 mg/kg (n = 3), 25 (n = 3), 50 (n = 4), 75 (n = 4), and 100 mg/kg (n = 2). Control animals (n = 6) received normal saline only. 90 min after infusion the cerebrum was obtained. The cerebral nitric oxide synthase...

... in newborn piglets. Measurements were made during three experimental periods: (1) control period with normal blood gases; (2) hypercapnia period, and (3) hypercapnia plus THAM period (THAM infusion: 1.65 mmol/kg/h). pH decreased and paCO 2 increased between control period (7.40 ± 0.05 and 45 ± 3 mm Hg...

...Marianne Thoresen; Andrew Whitelaw The objectives of this study were to measure the effect of acetazolamide on cerebral circulation, pulmonary elimination of CO 2 and cerebrovascular response to hypotension in newborn piglets. Eighteen anaesthetized newborn piglets were studied. A fontanelle...

...Péter Temesvári; Péter Hencz; Ferenc Joó; Erna Eck; Péter Szerdahelyi; Domokos Boda Acute, bilateral pneumothorax (PT) was produced in 14 newborn piglets. The clinical status of the operated and 14 control animals was monitored by measuring the arterial blood gases, acid-base balance and mean...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Newborn piglets Postnatal development Glomerular filtration Active...

... whether angiotensin II (Ang II) mediates the pulmonary vasoconstriction induced by acute hypoxia in newborn piglets. Methods: Eight unanesthetized chronically instrumented newborn piglets (mean ± SEM; age 6.6 ± 0.6 days; weight 2,181 ± 174 g) were randomly assigned to receive a saline solution or the Ang...

...Juan R. Ballesteros; Om P. Mishra; Jane E. McGowan To test the hypothesis that acute hypoglycemia leads to free radical induced alterations in cerebral mitochondria, newborn piglets were subjected to 2 h of insulin-induced hypoglycemia (blood glucose 1 mmol/l). The effects of free radicals were...

... hypothesized that this attenuation could also be achieved by applying the OLC during positive-pressure ventilation (PPV). After repeated whole-lung lavage, newborn piglets were assigned to one of three ventilation groups: (1) PPV OLC ; (2) HFOV OLC , or (3) conventional PPV (PPV CON ). After a ventilation...

...Xiang-Qing Yu; Sverre Medbø; OlaDidrik Saugstad The aim of the present study was to test whether hypoxanthine-xanthine oxidase (XO) induced a pulmonary vasoconstriction in newborn piglets, and whether this vasoconstriction could be attenuated or abolished by pretreatment of nitric oxide (NO) donor...

...Vigna Rajan; Kay D.A. Beharry; Paul Williams; Houchang D. Modanlou The objective of this study was to determine hemodynamic effects and pharmacokinetic profiles of fentanyl with continuous infusion in 1- to 3-day-old newborn piglets. The piglets (n = 6) were administered a loading dose of fentanyl...