... in the intermediate (mean GA 26.2 ± 1.6 weeks) saturation target group. Survival without morbidity was higher in the intermediate target group (adjusted odds ratio [aOR] 1.59; 95% CI: 1.04, 2.45). There was no difference in mortality between groups (aOR 0.81; 95% CI: 0.59, 1.11), in NEC, treated retinopathy, or brain...

... of the International Network for Evaluating Outcomes of Neonates (iNeo) Introduction: Despite advances in neonatal care, late-onset sepsis remains an important cause of preventable morbidity and mortality. Neonatal late-onset sepsis rates have decreased in some countries, while in others they have not. Our objective...

... these differences in assignment affect the identification and prediction of neonatal intensive care unit (NICU) mortality risk in US preterm infants. Methods: Birth data of infants admitted to NICUs from the Pediatrix Clinical Data Warehouse (2013–2018) were analyzed. Birth weight, length, and head circumference...

...–1.53]; p = 0.71). Conclusion: Neither the rates of SBI nor its associated composite outcome of death or NDI improved over time. A notable proportion of preterm infants with SBI faced redirection of care and subsequent mortality, while most survivors exhibited adverse neurodevelopmental challenges...

...Kee Thai Yeo; Guan Lin Goh; Woo Yeon Park; James L. Wynn; Khyzer B. Aziz Background: The discriminative utility of the neonatal sequential organ failure assessment (nSOFA) for early-onset sepsis (EOS) mortality in the neonatal intensive care unit (NICU) is unknown. Objectives: The objective...

..., preoperative treatments, and hospital background) to compare morbidities (bronchopulmonary dysplasia, intraventricular hemorrhage, necrotizing enterocolitis, and retinopathy of prematurity), mortality, total hospitalization costs, and other outcomes. For sensitivity analysis, we performed an overlap propensity...

...Jae Yoon Na; Donggoo Jung; Jong Ho Cha; Daehyun Kim; Joonhyuk Son; Jae Kyoon Hwang; Tae Hyun Kim; Hyun-Kyung Park Introduction: Prediction models assessing the mortality of very-low-birth-weight (VLBW) infants were confined to models using only pre- and perinatal variables. We aimed to construct...

...Tamara M Hundscheid; Eduardo Villamor-Martinez; Eduardo Villamor Introduction: Preterm birth represents the leading cause of neonatal mortality. Pathophysiological pathways, or endotypes, leading to prematurity can be clustered into infection/inflammation and dysfunctional placentation. We aimed...

... hypertension, extracorporeal membrane oxygenation (ECMO)-therapy, and mortality. We evaluated the discriminative values of the maximum OSI value and of mean OSI values with receiver operator characteristic (ROC) analysis and the area under the ROC curve. Results: In 42 infants with 49,473 OSI measurements...

... to in the content or advertisements. 2022 Neonatal intensive unit care Prematurity Neonate Quality of care Mortality Recent advances in perinatal and neonatal intensive care have resulted in improved survival of extremely preterm infants [ 1‒3 ]. However, the limited viability of infants born too...

... via area under the receiver operating characteristic curve (AUC) and compared to validated mortality prediction models and an external cohort of neonates. Results: Among 3,752 live-born extremely preterm infants (46% girls), in-hospital mortality was 18% ( n = 685). The median gestational age...

...Christoph Bührer; Günther Heller; Ulrich H. Thome Background and Objective: Results of five randomized controlled trials (RCT) sequentially published in 2010–2013 suggested that aiming for higher, as opposed to lower oxygen saturation targets, reduces rates of mortality in infants <28 weeks...

... outcomes. Results: Nine randomized controlled trials involving 2,553 infants were included. Six studies reported therapeutic efficacy, whereas 3 evaluated preventive benefits of zinc supplementation. Preventive studies suggest a protective effect of zinc supplementation on neonatal mortality rate (NMR...

...Cheyenne Mangold; Sarah Zoretic; Keerthi Thallapureddy; Axel Moreira; Kevin Chorath; Alvaro Moreira Introduction: Approximately 7,000 newborns die every day, accounting for almost half of child deaths under 5 years of age. Deciphering which neonates are at increased risk for mortality can have...

... ventricular systolic pressure <2/3 systemic), moderate (between 2/3 systemic and systemic), or severe (supra-systemic). Univariate and multivariate analyses were performed. Adjusted Poisson regression was used to assess the primary composite outcome of mortality or oxygen support at 30 days. Results...

..., instructions or products referred to in the content or advertisements. Carrying devices Cradle History Mortality Neonatal brain Outcome Vestibular stimulation “Three forms of rocking for babies have been devised by nursemaids, in cradles, in swings, and in their own arms. Now when we must...

... population for morbidity and mortality in the neonatal period. Variability in practices and outcomes between centers has been acknowledged. Multicenter benchmarking studies are useful to detect areas of improvement and constitute an interesting research tool. Objectives: The aim of the study was to determine...

.... Objectives: We aimed to identify the association between mortality or a composite mortality/major morbidity outcome in preterm infants with 1-min, 5-min, and sum 1 + 5-min Apgar scores. Methods: Seven-year retrospective data was analysed on neonates born <32 weeks gestation in a regional neonatal centre...

... <1,500 g) has been rarely reported. Objectives: The aim of this study was to investigate the epidemiology of congenital anomalies in VLBWIs and the association with early mortality and major morbidities. Study Design: A prospective cohort study was performed using data collected from 70 centers...

...Soon Min Lee; Myung Hee Lee; Yun Sil Chang; and the Korean Neonatal Network Background: A simple predictive indicator of mortality and morbidities is essential to assess neonatal illness severity and plan proper management. Objective: This study aimed to test the time-dependent performance...