... Meconium aspiration syndrome Lung injury Brain injury Outcome Meconium aspiration syndrome (MAS) is the most serious complication of meconium-stained amniotic fluid (MSAF) and the most critical respiratory disease in full-term infants. The incidence rate of MAS varies widely, ranging from 0.66...

... in the stem cell field of research, in combination with the continuous expansion in our knowledge of stem cell biology [for reviews, see [ 11,12 ]], has enabled researchers to explore the role of stem cells in neonatal lung injury. Indeed, several studies in experimental animal models have provided convincing...

... disease Inflammation Interleukin-6 Lung Lung injury Lung lavage Preterm infants Soluble gp130 Soluble IL-6 receptor Pre- and post-natal infection, along with other injurious factors such as mechanical ventilation and oxygen [ 1,2 ], contribute to pulmonary inflammation in preterm infants...

... gas exchange, lung mechanics and lung injury. Methods: Preterm lambs at 128 days gestational age were studied. HFJV (7 Hz, PEEP 8 cm H 2 O, PIP HFJV 40 cm H 2 O, FiO 2 0.4) with superimposed CMV breaths (PIP CMV 25 cm H 2 O, rate 5 breaths/min) was commenced after delivery and continued for 2 h. CMV...

... from any ideas, methods, instructions or products referred to in the content or advertisements. Hypocapnia Pulmonary hyperventilation Extracorporeal membrane oxygenation Lung injury Pulmonary hypertension Original Paper Biol Neonate 1993;64:254-260 W.A.A. Klöpping-Ketelaarsa M. Havenithb...

...Henry J. Rozycki Alveolar macrophage (AM) production of pro-inflammatory cytokines has been associated with the development of acute and chronic lung injury. However, the role of AM-derived IL·1Β in the development of bronchopulmonary dysplasia has not been extensively examined. To determine...

... surfactant with the host’s alveolar environment. This, in turn, may dictate how a specific patient responds to a particular surfactant treatment strategy. It is suggested that patients at an early stage of lung injury will benefit from aerosolized exogenous surfactant whereas large quantities of an instilled...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Bilirubin Lung injury Oxygen radicals Antioxidants Biol Neonate 1991:60:320-326 Bilirubin as an Antioxidant: Effect...

...Veniamin Ratner; Siarhei Slinko; Irina Utkina-Sosunova; Anatoly Starkov; Richard A. Polin; Vadim S. Ten Background: Premature infants with lung injury often experience intermittent episodes of hypoxemia. Objective: This study investigates whether intermittent hypoxemia exacerbates oxidative stress...

... Ziekenhuis Maastricht, Maastricht, The Netherlands Key Words Lung injury Mechanical ventilation Cytokines Bronchopulmonary dysplasia Abstract We review information about how the preterm lung can be injured with the initiation of mechanical ventilation at birth. Although multiple variables...

..., pulmonary mechanics, and histopathology were used to define the degree of lung injury. The mice were subjected to brief (10 min/day) and intermittent (10 days) hypoxic stress (8% O 2 ) at different stages of the development of hyperoxia-induced lung injury. At 8 weeks of life, the neurofunction was assessed...

... Extracorporeal membrane oxygenation Lung injury Cytokines Respiratory failure Bronchoalveolar lavage Abstract Background: It is likely that the imbalance between the pro- and anti-in ammatory cytokines will determine the outcome in infants with severe respiratory failure receiving extracorporeal membrane...

...: To investigate the possible protective effects of human intravenous immunoglobulin G (IVIG) on the hypertensive and inflammatory lung injury in severe neonatal meconium aspiration. Methods: Eleven newborn (10–12 days old) ventilated and catheterized piglets that received an intratracheal bolus (3 ml/kg) of a 65...

... to in the content or advertisements. Respiratory distress syndrome Prematurity Chronic lung disease Mechanical ventilation Lung injury Biol Neonate 2001;80(suppl 1):7 13 Bronchopulmonary Dysplasia and Surfactant Eduardo Bancalari Teresa del Moral Department of Pediatrics, Division of Neonatology...

... such intervention. Preconditioning the lungs with anisosmotic solutions may allow the cells to recruit excess plasma membrane and thus be more resistant to ventilator-induced lung injury. Osmolar concentration Cell membrane Mechanical stress Lung injury Review Biol Neonate 2004;85:290 292 DOI: 10.1159...

... is both safe and effective up to 72 h in premature lambs. 24 9 2003 Perfluorochemical fluid Liquid ventilation Premature lambs Gas exchange Lung injury Uptake and biodistribution Acute respiratory distress syndrome © 2003 S. Karger AG, Basel 2003 Copyright / Drug Dosage...

... W Lung injury W Respiratory distress syndrome W Bronchopulmonary dysplasia W Lamellar bodies Abstract We evaluated surfactant treatment effects on lung morphology and alveolar type II cells of preterm ventilated lambs. Lambs were ventilated for 10 h following treatment of the right lung with natural...