... clarification have been published on diagnostic lung ultrasound (LUS) signs of transient tachypnea of the neonate (TTN) in previous cross-sectional, single-center studies. This work was conducted to correlate clinical and imaging data in a longitudinal and multicenter fashion. Methods: Neonates...

...Sigrid Bjørnstad; Ragnhild E. Paulsen; Aage Erichsen; Joel C. Glover; Borghild Roald Background: Antenatal corticosteroids and surfactant replacement therapy have dramatically reduced mortality caused by lung disease in premature babies. Knowledge about mechanisms regulating epithelial...

... to produce both pro- and anti-inflammatory effects in human diseases and animal models. The expression and functional activity of these molecules in lungs of preterm ventilated infants is unknown. Objectives: We investigated this pathway in preterm infants who were at risk of developing chronic lung disease...

... ventilation in the preterm neonatal lung and define its relationship to associated markers of inflammation. Methods: Inflammatory cell recruitment and expression of IL-6, sIL-6R, sgp130, IL-8 and monocyte chemotactic protein-1 (MCP-1) were quantified in tracheal aspirate fluid collected over a 14-day period...

...Anna Koskinen; Asta Laiho; Heikki Lukkarinen; Pekka Kääpä; Hanna Soukka Background: Maternal diabetes is associated with numerous adverse effects in fetal and neonatal organs, including the lungs. Objective: To investigate the effects of intrauterine hyperglycemia on neonatal lung biological...

...Jasper V. Been; Bea Zoer; Nico Kloosterboer; Carolina G.A. Kessels; Luc J.I. Zimmermann; J. Freek van Iwaarden; Eduardo Villamor Background: Prenatal hypoxia is an important cause of intrauterine growth retardation that affects fetal lung maturation, although previous studies have rendered...

...Milagros Malicdem; Wiley Taylor; Mary Goerke; Uday Devaskar The extracellular matrix is important in the cellular differentiation and morphogenesis of the lung. The basement membrane (BM), an integral part of the extracellular matrix, is composed primarily of type IV collagen. The metabolism...

...A. Labbé; B. Delcros; P. Déchelotte; C. Nouailles; G. Grizard The specific binding capacities for human prolactin (hPRL) and human growth hormone (hGH) were examined in human lung membrane preparations at different developmental stages. A parallel study was carried out on rabbit lung preparations...

... in tissues of neonatal rats. Beside some minor differences in the development of lipoprotein lipase in some tissues like brown adipose tissue and lungs, we found quite remarkable differences between both strains in the development of lipoprotem lipase and hepatic lipase activities in the liver. In 1-day-old...

... of bronchopulmonary dysplasia of the premature infant. Recent work showed that the fetal rat lung retinyl palmitate stores were high preterm, but fell abruptly between 21 days of gestation and postpartum. This report extends this observation by showing that lung retinyl palmitate also decreases after cesarean section...

...Francis H.C. Tsao 5′-Nucleotidase was assayed in the membrane fractions isolated from rabbit lung homogenate. The enzyme activity was measured from the rate of hydrolysis of [U- 14 C]cytidine 5′-monophosphate (CMP). The optimal pH of the rate of hydrolysis is around 8.0 and the enzyme activity...

... day of postnatal age. The vitamin A contents of fetal hepatic and extra-hepatic tissues (lung, heart and brain) were increased with the age of pups and this increase was observed to be dependent on the supply of vitamin A to the mother. Biol. Neonate 50: 345-350 (1986) © 1986 S. Karger AG, Basel 0006...

...Jacques R. Bourbon; Philip M. Farrell; Edith Doucet; Jeannette Brown; Cécile Valenza The paper describes a comprehensive assessment of lung growth and biochemical maturation in the fetal and early postnatal rat. Fetal lung grew faster than whole body between gestational day 16.5 and term. Cell...

..., spleen, pancreas, sternum and thymus during the period of gestation studied. It was highest in skeleton (ribs and vertebral bodies), kidney and lung from day 19 onwards. In the cytosol of these latter tissues, a high affinity (K d 0.7–3.6 × 10 –– 10 M ), low capacity [ 3 H]1,25-(OH) 2 D 3 binding...

... to the early extra-uterine developmental stages of the rat. To elucidate the question to what extent the development of the lung is related to the developmental timing of birth, we have studied some enzymes involved in the de novo synthesis of phosphatidylcholine. Of the enzymes studied, cholinephosphate...

... and cholesterogenesis was studied with the help of sodium-1- 14 C-acetate incorporation. The heart, liver and lung showed impaired lipogenesis while in the brain only cholesterogenesis was affected. 18 9 2009 © 1984 S. Karger AG, Basel 1984 Copyright / Drug Dosage / Disclaimer Copyright: All rights...

... Malic enzyme Isocitrate dehydrogenase Brain Heart Liver Lung Biol. Neonate 46: 291-295 (1984) © 1984 S. Karger AG. Basel 0006-3126/84/0466-0291 $2.75/0 Vitamin A and Biochemical Development II. Effect of Postnatal Excess Vitamin-A Administration on the Activity of Pyridine Nucleotide-I.inked...

...Philip M. Farrell; Michael F. Epstein; Alan R. Fleischman; Gary K. Oakes; Ronald A. Chez The two pathways for denovo lecithin (phosphatidylcholine) biosynthesis, choline incorporation (I) and phosphatidylethanolamine methylation (II), were examined simultaneously in lung and other tissues of Rhesus...

...Margit Hamosh; Morton R. Simon; Darlene K. Mullon; Paul Hamosh The uptake and metabolism of 3 H-ρalmitate, 14 C-choline, 14 C-proline and 3 H-glucosamine were studied in lung slices prepared from rats aged 2–12 days. Palmitate incorporation increased from 18.2 ± 2.8 nmol/mg protein/h 2 days before...

... lipase activity of the lung. Cumulative maternal weight gain from days 15–21 of gestation was 80 ± 4.0 g in control and 30 ± 10 g in dexamethasone-treated rats. Fetal weight at 22 days of gestation and 1 day after birth was 5.5 ± 0.39 and 8.6 ± 0.30 in control and 4.65 ± 0.26 and 5.9 ± 0.34...