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Keywords: Lipopolysaccharide
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Journal Articles
Journal: Neonatology
Neonatology (2018) 113 (3): 212–220.
Published Online: 23 December 2017
... when infection is a comorbidity to hypoxic-ischaemic (HI) brain injury. Gram-negative and gram-positive species activate the immune system through different pathogen recognition receptors and subsequent immunological systems. In rodent models, gram-negative (lipopolysaccharide [LPS]) and gram-positive...
Journal Articles
Journal Articles
Journal: Neonatology
Neonatology (2008) 93 (2): 87–100.
Published Online: 16 August 2007
... on the effects of sepsis, Affymetrix gene profiling (8,475 genes) was done on RNA isolated from CBMNC and APBMNC without and after incubation with 100 ng/ml lipopolysaccharide (LPS). Results: We demonstrated significant alterations in the expression of 108 CBMNC and APBMNC genes compared with basal levels, 188...
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Journal Articles
Journal Articles
Journal: Neonatology
Biology of the Neonate (2006) 90 (4): 258–267.
Published Online: 20 November 2006
... the effect of acute episodes of hypoxia alone or in combination with lipopolysaccharide (LPS) exposure on plasma and brain allopregnanolone concentrations in lambs 10–21 days old. Also, to examine plasma levels of cortisol and the cytokines, tumour necrosis factor-α and interleutkin-6 after these challenges...
Journal Articles
Journal Articles
Journal: Neonatology
Biology of the Neonate (1999) 76 (Suppl. 1): 19–21.
Published Online: 17 November 2004
... host defense. We have found that SP-A exhibits different interactions with distinct serotypes of lipopolysaccharides and affects differently their elicited cellular responses by a direct interaction with the lipopolysaccharide receptor CD14. In addition to the basic aspects, lung collectins as clinical...
Journal Articles
Journal: Neonatology
Biology of the Neonate (2001) 80 (3): 186–192.
Published Online: 04 October 2001
... to lipopolysaccharide (LPS) was investigated and compared to that of adults. MC were incubated with various doses of LPS, and the cytokine level in the supernatants was tested. CD14 receptors on MC and the intensity of their expression were analyzed. MC of preterm and term neonates and adults responded to LPS with low...
Journal Articles
Journal: Neonatology
Biology of the Neonate (2001) 80 (2): 124–132.
Published Online: 15 August 2001
... the mechanism of the clinical benefit of steroids in babies. Our results showed that dexamethasone, budesonide and rIL-10 significantly inhibited both IL-6 and TNF-α production in the THP-1 cell line stimulated by lipopolysaccharide and Ureaplasma urealyticum antigen. Similar effects were found in macrophages...
Journal Articles
Journal: Neonatology
Biology of the Neonate (2000) 78 (3): 207–211.
Published Online: 14 October 2000
... intraperitoneal (ip) injection as follows: group 1: 0.1 ml saline; group 2: 0.1 mg/kg Salmonella enteritidis lipopolysaccharide (LPS); group 3: 1 mg/kg of anti-TNFα antibodies (Ab); group 4: 0.1 mg/kg of LPS and 1 mg/kg of Ab. We found that in group 2, LPS induced shock, demonstrating hypoglycemia...
Journal Articles
Journal: Neonatology
Biology of the Neonate (1999) 76 (5): 291–300.
Published Online: 07 October 1999
...) inhibited PASMC proliferation in a dose-dependent manner with associated cGMP increases, while NO scavengers (carboxy-PTIO), iNOS stimulators (interleukin-1β, lipopolysaccharide), and iNOS inhibitors (aminoethylisothiourea) did not affect proliferation or cGMP. No changes in apoptosis were found...
Journal Articles
Journal: Neonatology
Biology of the Neonate (1998) 74 (5): 372–375.
Published Online: 30 September 1998
...K.M. Dziegielewska; N.A. Andersen We show that fetuin, a fetal glycoprotein present in fetal plasma in concentrations substantially higher than in the adult, can exert a protective function against ill-effects of the bacterial endotoxin, lipopolysaccharide (LPS), in pregnancy. The concentration...