... Glucose 6 phosphate dehydrogenase deficiency Kernicterus Neonatal hyperbilirubinemia Neonatal jaundice is a common condition in the first week of life. Mild unconjugated hyperbilirubinemia affects approximately 50–70% of term infants, reflecting the normal transition from pre- to postnatal life...

... to in the content or advertisements. Bilirubin Kernicterus Registry Database Next generation sequencing One of the potentially most devastating adverse outcomes of neonates is acute bilirubin encephalopathy (ABE). ABE involves damage, which is frequently permanent, to a neonate’s central nervous...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Neonatal jaundice Severe hyperbilirubinemia Acute bilirubin encephalopathy Kernicterus Low- and middle-income countries The prevalence...

... of kernicterus. Methods: A review of the existing guidelines and literature on the management of neonatal hyperbilirubinemia worldwide was conducted to identify criteria and underlying factors for initiating ET. Results: There is a dearth of evidence from randomized clinical trials to support clear criteria...

...: Hyperbilirubinemia, hemolysis, and increased bilirubin neurotoxicity. Semin Perinatol 2014;38:439-437. 5. Christensen RD, Yaish HM, Nussenzveig RH, et al: Acute kernicterus in a neonate with O/B blood group incompatibility and a mutation in SLC4A1. Pediatrics 2013;132:e531-e534. 6. Christensen RD, Yaish HM...

..., instructions or products referred to in the content or advertisements. Erythrocyte Kernicterus Jaundice Neonate Hemolysis Glucose 6-phosphate dehydrogenase Severe jaundice is the most common condition requiring re-hospitalization during the first week after birth [ 1,2 ]. Unfortunately, most...

...Michael Kaplan; Ruben Bromiker; Cathy Hammerman Despite efforts to eliminate permanent and irreversible brain damage due to bilirubin encephalopathy and kernicterus, these conditions continue to accompany us into the third millennium. This phenomenon occurs not only in developing countries...

...Numan Nafie Hameed; Alaa’ Muhamed Na’ ma; Rohan Vilms; Vinod K. Bhutani Background: Severe neonatal hyperbilirubinemia, when unmonitored or untreated, can progress to acute bilirubin encephalopathy (ABE). Initiatives to prevent and eliminate post-icteric sequelae (kernicterus) are being implemented...

...M. Moll; R. Goelz; T. Naegele; M. Wilke; C.F. Poets Two extremely low birth weight (ELBW) infants developed characteristic signs of kernicterus at 4 and 8 months corrected age despite only moderate neonatal hyperbilirubinemia (peak serum bilirubin <10 g/dl) and phototherapy being applied...

...Thor Willy Ruud Hansen; William J. Cashore The mechanism for the preferential distribution of bilirubin to basal ganglia (‘kernicterus’) is unknown. We hypothesized that differences in bilirubin clearance rates between brain regions might explain this phenomenon. Bilirubin [30mg/kg over 5 min...

... the groups in either of these measures. We conclude that in young rats, hemolytic anemia does not increase the acute entry of bilirubin into brain, nor does it affect the clearance of bilirubin from brain. 30 9 2009 Kernicterus Bilirubin encephalopathy Bilirubin kinetics Hemolytic anemia...

.... The purpose of this study was to confirm the existence of bilirubin metabolism in the brain and to examine the possible contribution of such an activity to the bilirubin staining pattern characteristic of kernicterus. Mitochondrial membrane fractions were prepared in 0.32 M sucrose from whole rat brains...

...Eli Chan A study was made of the effect of berberine, the major ingredient of the Chinese herb huanglian (coptis chinensis) reported to pose some risk for kernicterus among jaundiced newborn Chinese infants, on the protein binding of bilirubin, using the peroxidase kinetic method. Berberine...

.... Kernicterus Bucolome Cerebellar bilirubin Granule cell Gunn rat Cerebellum Biol Neonate 1989;55:119-123 ©1989 S. Karger AG, Basel 0006-3126/89/0552-0119Î2.75/0 Mode of Bilirubin Deposition in the Cerebellum of Developing Jaundiced Gunn Rats (With 1 color plate) S. Aono, R. Semba, H. Sato, S...

... to in the content or advertisements. Hyperbilirubinemia Phototherapy Unbound bilirubin Kernicterus Bilirubin-albumin binding Biol. Neonate 39: 295-299 (1981) Effects of Phototherapy on Serum Unbound Bilirubin in Icteric Newborn Infants Hajime Nakamura, Yokci Lee. Yoshiyuki Uelani, Yoshiki Kitsunezuka...

.... Sephadex-gel filtration Bilirubin-albumin binding Kernicterus Gunn rats Biol. Neonate 33: 13 17 (1978) Sephadex-Gel Filtration (SGF) in Infant and Adult Gunn Rats L. Ballowitz, F. Hanefeld, R. Jerofke, P. Keller, J. Korn and U. Schweitzer Kaiserin Auguste Victoria Haus, Children s Hospital, Free...

...Derek R. Pledger; Jean M. Scott; Alan Belfield A retrospective survey of neonatal postmortems over a 10-year period was made to establish the incidence of kernicterus and the associated laboratory abnormalities. Cases with evidence of kernicterus without hyperbilirubinaemia were found to have...

... newborns (both prematures and full terms) presenting rhesus incompatibility. Kernicterus was observed in seven cases and only three occurred in the TB group above 20 mg/100 ml; 57 cases had FB equal to or above 0.1 mg/100 ml and all kernicterus fell into this category. In the other 55 cases in which FB...

...Vinod K. Bhutani; M. Jeffrey Maisels; Ann R. Stark; Giuseppe Buonocore Kernicterus is still occurring but should be largely preventable if health care personnel follow the recommendations listed in this guideline. These recommendations emphasize the importance of universal, systematic assessment...

...Steven M. Shapiro; Sompong Sombati; Angela Geiger; Ann C. Rice Background: Bilirubin encephalopathy or kernicterus is a potentially serious complication of neonatal hyperbilirubinemia. The mechanism of bilirubin-induced neurotoxicity is not known. Many neurological insults are mediated through NMDA...