...Kenji Ichinomiya; Kenichi Maruyama; Takahiro Inoue; Aya Koizumi; Fumitaka Inoue; Kazuyo Fukuda; Yu Yamazaki; Hirokazu Arakawa Background: Hepcidin, an iron-regulatory hormone, plays a key role in preventing iron overload. Few studies have investigated the regulation of hepcidin in low-birth-weight...

...Nisreen A. Alwan; Janet E. Cade; Harry J. McArdle; Darren C. Greenwood; Helen E. Hayes; Etienne Ciantar; Nigel A.B. Simpson Background: In animal studies, iron deficiency during pregnancy has been linked to increased offspring cardiovascular risk. No previous population studies have measured...

... of recombinant human erythropoietin (rhEp) in very-low-birth-weight infants will require a better understanding of rhEp’s pharmacodynamic effects including its interaction with iron in stimulating erythropoiesis. The purpose of this study was to determine the effects of chronic rhEp administration on plasma iron...

... and from 8 with neural tube defect (NTD) pregnancies. Folate was measured by microbiological assay, vitamin B 12 by a radiobinding method, and zinc, copper and iron by atomic absorption spectrophotometry. We found that the mean amniotic fluid nutrient levels of normal pregnancies were 24.7nmol/l for folate...

...James K. Friel; Derek Matthew; Wayne L. Andrews; Craig T. Skinner Meconium samples from 23 preterm infants (birth weight = 1,097 ± 359 g; gestational age 29 ± 3 weeks, mean ± SD) and 27 full-term infants (3,453 ± 476 g; 39.5 ± 1 weeks) were analyzed for zinc, copper, manganese, chromium and iron...

...Yehuda Matoth; Rina Zaizov Materno-fetal transfer of iron was studied in the rat under various conditions affecting maternal iron kinetics. A low maternal plasma iron turnover rate (PITR), whether due to a low serum iron concentration or a reduced plasma volume, was associated with a decrease...

...N. Kaufman; J.C. Wyllie 59 Fe was given orally to fetal rats from day 18 to 21 to determine whether there was evidence for regulation of iron absorption prior to birth. The fetal rat was able to absorb 59 Fe. The quantity absorbed, however, declined significantly towards term. We suggest...

...Kelsey J. Kleven; Sharon E. Blohowiak; Pamela J. Kling Background: Zinc protoporphyrin/heme (ZnPP/H) ratios are indicators of incomplete erythrocyte iron delivery. ZnPP/H is more sensitive than measures of iron stores, such as plasma ferritin, in identifying early pre-anemic iron-deficient...

...Ashajyothi M. Siddappa; Raghavendra Rao; Jeffrey D. Long; John A. Widness; Michael K. Georgieff Background: Serum ferritin measurements are used in clinical populations to estimate total body iron stores and the risk of subsequent iron deficiency or overload. The lack of normative newborn serum...

...Suzanne H. Dubuque; Bohuslav Dvorak; Suann S. Woodward; Robert S. McCuskey; Pamela J. Kling Anemia in premature infants is extremely common. Precise quantitation of iron status and determination of iron incorporation into erythrocytes are important in monitoring therapy for anemia in premature...

...Gerd M. Lackmann; Carsten Schnieder; Jürgen Bohner The diagnosis and treatment of fetal and neonatal diseases requires knowledge of gestational age-dependent reference ranges for most laboratory values. It was the aim of the present study to establish reference values for serum iron, transferrin...