... heterozygous variants are associated with primary congenital hypothyroidism, respiratory distress and neurologic symptoms such as benign hereditary chorea – the brain-lung thyroid syndrome. Surfactant Diffuse developmental disorder of the lung Infant NKX2.1 Pulmonary hypertension...

...Michael Obladen Abandoning infants was a heritage of the Roman Empire. Foundling hospitals were established in Italy earlier and in greater number than in other countries; their goal was to prevent infanticides. The Foundling Hospital in Rome, established in the Santo Spirito Church in 1204, paved...

...) of neonates investigators Introduction: Our objective was to evaluate the temporal trend of systemic postnatal steroid (PNS) receipt in infants of 24–28 weeks’ gestational age, identify characteristics associated with PNS receipt, and correlate PNS receipt with the incidence of bronchopulmonary dysplasia (BPD...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. COVID-19 Outcomes Infant Preterm Maternal positivity...

... Durán-Fernández-Feijóo; Patricia Morales-Arandojo; Marcelino Pumarada-Prieto; Ignacio Oulego-Erroz Introduction: The lung ultrasound score (LUS) has been suggested to predict moderate-severe bronchopulmonary dysplasia (msBPD) in preterm infants. We aimed to assess LUS evolution after birth in preterm...

...Diane Snyers; Sophie Tribolet; Vincent Rigo Aim: Pain management is important for newborns’ immediate and long-term well-being. While intranasal analgesia and sedation have been well studied in children, their use could be extended to term and preterm infants. This systematic review aims to assess...

...Seong Phil Bae; Ee-Kyung Kim; Jungha Yun; Young Mi Yoon; Seung Han Shin; Su Yeon Park Background: Retinopathy of prematurity (ROP) is caused by prenatal sensitization and postnatal insults to the immature retina. This process can be associated with the postnatal growth of preterm infants. We...

...Olli Turta; Marta Selma-Royo; Himanshu Kumar; Maria Carmen Collado; Erika Isolauri; Seppo Salminen; Samuli Rautava Objective: The aim of the study was to investigate the impact of intrapartum antibiotic treatment (IAT) on the compositional development of gut microbiota in healthy term infants...

...Linda Gai Rui Chen; Po-Yin Cheung; Brenda Hiu Yan Law Background: Stepwise lung recruitment maneuvers (LRMs) may be used in ventilated preterm infants. However, its use in high-frequency oscillation with volume guarantee (HFO-VG) is not well studied. Methods: Preterm infants treated with HFO-VG who...

...Jessica Alexandra Kimpton; Amit Verma; Devangi Thakkar; Sophia Teoh; Aarti Verma; Chinthika Piyasena; Cheryl Battersby; for the Neonatal Trainee-Led Research and Improvement Projects (NeoTRIPs) Introduction: The NICE guideline CG149 has increased the number of well infants receiving antibiotics...

...Stacey Chi-Yan Lo; Risha Bhatia; Calum T. Roberts Introduction: Exposure to mechanical ventilation (MV) is a risk factor for bronchopulmonary dysplasia (BPD) in very preterm infants (VPTIs). We assessed the impact of a quality improvement (QI) bundle in VPTIs (<32 week gestation) on exposure...

...Laure Dombrecht; Filip Cools; Joachim Cohen; Luc Deliens; Linde Goossens; Gunnar Naulaers; Kenneth Chambaere; Kim Beernaert Background: The use of analgesics and sedatives to alleviate pain and discomfort is common in end-of-life care in neonates and infants. However, to what extent those drugs...

... infants. Therefore, our study aimed to evaluate the agreement between AT and RT measurements in very preterm infants. Methods: Preterm infants <32 weeks of gestational age were prospectively included. The infants’ body temperature (BT) was measured twice a day from day 1 to day 6. A paired t -test...

... advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Prematurity Infant Continuous positive...

...) infants at 36 and 44 weeks’ postmenstrual age (PMA), and at 1-year corrected postnatal age (cPNA). P I O 2 was decreased stepwise to achieve SpO 2 between 85 and 98%. Shift and shunt were calculated from paired SpO 2 /P I O 2 measurements using customized software. Results were examined cross-sectionally...

...Jonathan W. Davis; J. Jane Pillow; Matthew N. Cooper; Mar Janna Dahl Background: Bubble CPAP may be used in infants with suspected or confirmed COVID-19. Electrostatic filters may reduce cross infection. This study aims to determine if including a filter in the bubble CPAP circuit impacts stability...

...Rebecca Verhaeghe; Kandie George; Mark Westerman; Gordana Olbina; Diane McCann; Nermi Parrow; Elisa Pincus; Tomas Havranek; Robert E. Fleming Introduction: The basis for the superior absorption of iron from breast milk compared with infant formulas is unclear. The hormone hepcidin downregulates...

... of the Clinical Risk Index for Babies (CRIB) II in predicting mortality and major short-term morbidities among very low birth weight infants (VLBWIs). Methods: This population-based prospective study from 67 Korean Neonatal Network centers performed between 2013 and 2016 included 5,296 VLBWIs with CRIB II...

...Maureen C. Reilly; Sunita Vohra; Valeria E. Rac; Denise Zayack; John Wimmer; Michael Vincer; Karla Ferrelli; Alex Kiss; Roger F. Soll; Michael Dunn Background: The treatment effect of occlusive wrap applied immediately after delivery in infants born 24–28 weeks’ gestation has been studied...

... infants; OR = 1.16, 95% CI = 0.86–1.57) but was associated with visual-motor impairment ( n = 508; OR = 3.46, 95% CI = 1.13–10.57) and executive dysfunction ( n = 463; OR = 2.50, 95% CI = 1.20–5.22). In mid-childhood, neonatal hypoglycaemia was associated with neurodevelopmental impairment ( n = 54...