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Keywords: Ibuprofen
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Journal: Neonatology
Biology of the Neonate (2007) 91 (4): 318.
Published Online: 07 June 2007
... with minimal side effects and about the choice of the drug continues. Recent evidence demonstrated that ibuprofen is a reasonable alternative to indomethacin for early treatment of a PDA. It has different effects on regional circulations and influences cerebral circulation and oxygen delivery to the brain...
Journal Articles
Journal: Neonatology
Biology of the Neonate (2004) 86 (4): 235–239.
Published Online: 12 November 2004
...Nazeeh Hanna; Sarah Graboski; Debra L. Laskin; Barry Weinberger Background: Ibuprofen is a cyclooxygenase inhibitor that is effective in treating patent ductus arteriosus in preterm infants. However, recent trials have suggested that it may increase the risk of developing necrotizing enterocolitis...
Journal Articles
Journal: Neonatology
Biology of the Neonate (2003) 84 (3): 187–193.
Published Online: 24 September 2003
... (an index of cerebral intravascular oxygenation). In 10 infants the study was repeated 1 h after intravenous administration of 10 mg/kg ibuprofen as prophylaxis against PDA. Withdrawal and infusion via the UVC caused significant MABP and concordant HbD and CBV changes. Smaller modifications were seen...
Journal Articles
Journal: Neonatology
Biology of the Neonate (2002) 82 (2): 73–77.
Published Online: 07 August 2002
...H. Bessler; S. Ziyada; M. Bergman; I. Punsky; L. Sirota The in vitro effect of indomethacin (IM) and ibuprofen (IB) on the production of the interleukin-1 receptor antagonist (IL-1ra) by cord blood mononuclear cells (CBMC) from preterm newborns was compared to that of peripheral blood mononuclear...
Journal Articles
Journal: Neonatology
Biology of the Neonate (2001) 79 (2): 103–108.
Published Online: 12 February 2001
...L. Sirota; D. Shacham; I. Punsky; H. Bessler The in vitro effect of ibuprofen (IB) on the production of the proinflammatory cytokines interleukin (IL) 1β, IL-6, and tumor necrosis factor alpha (TNF-α) and the anti-inflammatory cytokine IL-10 by cord blood mononuclear cells from preterm newborns...