... and hyperbilirubinemia in a neonate with pyruvate kinase deficiency (PKD) arising from compound heterozygous PKLR mutations. The nature of the thrombocytopenia in this patient created considerable diagnostic uncertainty, which was ultimately resolved by whole-exome sequencing. This case emphasizes that inherited red...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Hyperbilirubinemia Medical Point-of-care bilirubin Bilistick® system (BM-BS 1.0 – FW version 2.0.1) Transcutaneous bilirubin Jaundice due to elevated levels...

...Thivia Jegathesan; Joel G. Ray; Vinod K. Bhutani; Charles Donald George Keown-Stoneman; Douglas M. Campbell; Vibhuti Shah; Howard Berger; Robin Z. Hayeems; Michael Sgro; for the NeoHBC Introduction: As preterm infants are susceptible to hyperbilirubinemia, they require frequent close monitoring...

... to screening for hyperbilirubinemia with more careful use in preterm infants born at <33 weeks’ gestation, as TcB approaches treatment thresholds. Its underestimation of TSB after the initiation of phototherapy warrants the use of TSB for clinical decision-making after the initiation of phototherapy...

... from Salt Lake City, UT, USA. This newborn presented with severe hyperbilirubinemia (29.8 mg/dL or 510 μmol/L) and marked hemolysis evidenced by elevated end-tidal carbon monoxide concentration (5.9 ppm, normal <1.7 ppm). Despite a very low prevalence of G6PD deficiency in Hispanic populations, we...

...Ashwani Bhatia; Mei Chien Chua; Rowena dela Puerta; Victor Samuel Rajadurai Background: Hemolytic hyperbilirubinemia due to blood group incompatibility or glucose-6-phosphate dehydrogenase deficiency (G6PD) is a common cause of significant hyperbilirubinemia. Hemolysis in a hyperbilirubinemic...

... hyperbilirubinemia. [email protected] 26 06 2019 17 08 2019 4 10 2019 © 2019 S. Karger AG, Basel 2019 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form...

...Sota Iwatani; Jordan Burgess; Flora Kalish; Ronald J. Wong; David K. Stevenson Background: Increased bilirubin production due to hemolysis can lead to severe neonatal hyperbilirubinemia and, if left untreated, to bilirubin neurotoxicity. Post-cardiac surgery newborns have been shown...

...Michael Kaplan; Ronald J. Wong; David K. Stevenson Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a common enzyme deficiency affecting more than 300 million individuals worldwide. Extreme neonatal hyperbilirubinemia, with its severe sequelae of bilirubin neurotoxicity...

...Nazli Kuter; Nese Aysit-Altuncu; Gurkan Ozturk; Eren Ozek Background: In high-risk newborns indirect hyperbilirubinemia can lead to acute bilirubin encephalopathy and kernicterus. Despite the current therapeutic modalities, preventing or reversing the neurotoxicity cannot be achieved in all infants...

...Amy R. Borden; Katie M. Satrom; Paul Wratkowski; Thomas N. George; Constance A. Adkisson; Hendrik J. Vreman; Austin P. Johnson; Kent J. Nichols; Tina M. Slusher Background: Phototherapy (PT) is widely used to prevent and treat severe hyperbilirubinemia and its associated risks for both acute...

...Amandine Rubio; Chloé Epiard; Maya Gebus; Michel Deiber; Sylvain Samperiz; Céline Genty; Anne Ego; Thierry Debillon Background: Transcutaneous bilirubin (TcB) is a validated test for systematic screening of neonatal hyperbilirubinemia and monitoring term and near-term infants under phototherapy...

... the patient's total bilirubin level was 255 μmol/l. Intermittent episodes of hyperbilirubinemia occurred without phototherapy, with the total bilirubin level reaching 335 μmol/l on day 19. A 3-day regimen of phenobarbital was administered and on day 24 his total bilirubin level was 180 μmol/l. The patient...

...: Hyperbilirubinemia, hemolysis, and increased bilirubin neurotoxicity. Semin Perinatol 2014;38:439-437. 5. Christensen RD, Yaish HM, Nussenzveig RH, et al: Acute kernicterus in a neonate with O/B blood group incompatibility and a mutation in SLC4A1. Pediatrics 2013;132:e531-e534. 6. Christensen RD, Yaish HM...

...I. Mohamed; A.C. Blanchard; E. Delvin; J. Cousineau; A. Carceller Background: The American Academy of Pediatrics has recommended a systematic assessment before discharge for the risk of severe hyperbilirubinemia. Plotting total serum bilirubin (TSB) or transcutaneous bilirubin (TcB) on a TSB hour...

...Mark J. Gotink; Manon J. Benders; Selma W. Lavrijsen; Rob Rodrigues Pereira; Christian V. Hulzebos; Peter H. Dijk Background: The occurrence of severe neonatal hyperbilirubinemia (SH) is partly attributed to nonhospitalized perinatal care. The Netherlands have a high frequency of home births...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Hemolytic disease of the newborn Cholestasis Hyperbilirubinemia Intrauterine blood transfusion Iron overload...

... to thrive, hypoglycemic seizures, and coma in infancy or early childhood. Here we report the case of a 17-day-old newborn diagnosed with FGD type 1 who presented with hyperbilirubinemia and hyperpigmentation, a sign which was erroneously assumed to be due to prolonged phototherapy by the referring physician...

...M. Moll; R. Goelz; T. Naegele; M. Wilke; C.F. Poets Two extremely low birth weight (ELBW) infants developed characteristic signs of kernicterus at 4 and 8 months corrected age despite only moderate neonatal hyperbilirubinemia (peak serum bilirubin <10 g/dl) and phototherapy being applied...

... that the cephalocaudal color gradient is due to conformational changes in the newly formed bilirubin albumin complexes. Transcutaneous bilirubinometry Neonatal jaundice Hyperbilirubinemia Albumin binding Biology o f the Neonate Original Paper Biol Neonate 1997;71:357-361 A. Knudsen F. Ebbesen Department...