... no significant variation of plasma peptides until the first feed, except for somatostatin, which peaked at 4-5 h and declined thereafter. As assessed before and 1 h after feeding, the first meal tended to induce rises in plasma gastrin, cholecystokinin and pancreatic polypeptide, while the other peptides were...

...Per T. Sangild; Peter D. Cranwell; Linda Hilsted Gastric acid secretion, gastrin-releasing peptide (GRP)-stimulated gastrin secretion and concentrations of somatostatin in gastric tissues were studied in sucking pigs (n = 48). In addition, gastrin concentrations in plasma and antral tissue were...

... and antibodies to the H + /K + -ATPase (proton pump), intrinsic factor and gastrin in 25 fetuses (ranging from 13–28 weeks) and in 5 infants (2–21 weeks). Parietal cell activity was noted in the body, antrum and pyloric regions in all the fetal specimens examined. However, this activity was much more limited...

... simultaneously. Concentrations of the pancreatic hormones, insulin, glucagon and pancreatic polypeptide (PP) were similar in fetal and maternal blood. Gastrin and motilin were present in the fetal circulation but at about 30% (p < 0.05) and 60% (p < 0.01) of the maternal levels, respectively. In contrast...

...Ruo-Jun Xu; Y.-L. Mao; Man-Yin W. Tso It has been reported in the literature that a large quantity of gastrin is released into the gastric lumen in various species. This study was aimed to examine the stability of gastrin in the gastrointestinal (GI) lumen of pigs. Iodine-labelled little (G17...

...Ilan Zahavi; James Kelly; Grant Gall The role of gastrin and cholecystokinin (CCK) in postnatal development of the small intestine was examined in infant rabbits. Experimental animals received daily intraperitoneal injections of pentagastrin, 500 μg/kg, or CCK-octapeptide, 40 μg/kg, starting on day...

...Arthur Shulkes; Kenneth J. Hardy The effect of somatostatin infusion on basal plasma gastrin and pancreatic polypeptide (PP) has been examined in the chronically cannulated fetal sheep and in adult sheep. Somatostatin decreased basal gastrin and PP in the fetal sheep. Similar changes were seen...

... of the dams during their entire pregnancy. Pregnant rats were thus implanted subcutaneously with Alzet minipumps and received cerulein (0.25 μg kg –1 h –1 ), gastrin-releasing peptide (GRP; 0.18 μg kg –1 h –1 ), GRP antagonist (12 μg kg –1 h –1 ), pentagastrin (2.38 μg kg –1 h –1 ), L-365,260...

... and in amniotic fluid. During gestation, plasma peptide concentrations did not change in cows. Likewise, fetal plasma concentrations of cholecystokinin, somatostatin, secretin and vasoactive intestinal polypeptide showed no variation while those of gastrin, pancreatic polypeptide and gastric inhibitory...