...Srirupa Hari Gopal; Robert Tillman; James D. Hammond II; Joseph L. Hagan; Sharada H. Gowda; Nidhy P. Varghese; Caraciolo J. Fernandes Introduction: While a patent ductus arteriosus (PDA) helps offload the right ventricle in the acute congenital diaphragmatic hernia (CDH)-associated pulmonary...

... using early routine echocardiography performed by neonatologists. Methods: This study was a post hoc analysis of the Patent ductus arteriosus and Left Atrial Size Evaluation in preterm infants (PLASE) study, which is a prospective cohort study including preterm infants admitted to 34 tertiary neonatal...

...Anton Friis Mariager; Alberte Hammeken; Mikkel Malham; Anna Axelsson Raja; Anna Sellmer; Signe Levring Skjellerup; Raheel Altaf Raja; Johan Navne; Anne-Sophie Sillesen; Niels Vejlstrup; Henning Bundgaard; Kasper Karmark Iversen; Ester Garne; Dorthe Lisbeth Jeppesen Background: The ductus arteriosus...

...Stefano Ghirardello; Genny Raffaeli; Beatrice Letizia Crippa; Silvia Gulden; Ilaria Amodeo; Dario Consonni; Giacomo Cavallaro; Federico Schena; Fabio Mosca Background: The role of hemostasis in the closure of patent ductus arteriosus (PDA) in preterm infants is controversial. Objective: To assess...

...), the accuracy of EC has been verified. However, left-to-right patent ductus arteriosus (PDA) shunting is a concern because PDA shunts aortic flow to the pulmonary artery and may interfere with EC in measuring CO. Objective: To determine the agreement between EC and Echo in preterm infants with a hemodynamically...

...Ana Ledo; Marta Aguar; Antonio Núñez-Ramiro; Pilar Saénz; Máximo Vento Background: The therapeutic decision to close patent ductus arteriosus in preterm infants entails great uncertainty. Near-infrared spectroscopy is a noninvasive bedside technique used to monitor mixed regional oxygen saturation...

...Sorina R. Simon; Lieke van Zogchel; Maria Pilar Bas-Suárez; Giacomo Cavallaro; Ronald I. Clyman; Eduardo Villamor Background: Several cohort studies have shown an association between low platelet counts in the first day(s) of life and patent ductus arteriosus (PDA) in preterm infants. However...

...Jeroen J. van Vonderen; Arno A.W. Roest; Frans J. Walther; Nico A. Blom; Jan M.M. van Lith; Stuart B. Hooper; Arjan B. te Pas Background: During neonatal transition, ductus arteriosus (DA) flow changes from right-to-left to left-to-right and contributes considerably to the increase in pulmonary...

...Maria Pilar Bas-Suárez; Gema Esther González-Luis; Pedro Saavedra; Eduardo Villamor Background: Decreased platelet number and/or function are related to patent ductus arteriosus (PDA) in mice. Whether this is also the case in human infants remains controversial. Objectives: To investigate...

... to in the content or advertisements. Hyperinsulinemic hypoglycemia Diazoxide Ductus arteriosus Hyperinsulinemic hypoglycemia (HIH) is the most common cause of persistent hypoglycemia in neonates [ 1 ]. In addition, it can cause more serious psychomotor defects than other etiologies [ 2 ], so its...

... via the ductus arteriosus (DA) on regional oxygen saturation (rSO 2 ) of the brain and peripheral tissue during postnatal transition. Methods: Nested case-control study. In term neonates after elective cesarian section, rSO 2 of the brain and pre- and postductal peripheral tissue were measured 15 min...

...Barbara Baragatti; Francesca Scebba; Daria Sodini; Eleonora Pagni; Enrica Ciofini; Daigen Xu; Flavio Coceani Background: Microsomal prostaglandin E synthase-1 (mPGES1) is critical for prostaglandin E 2 formation in ductus arteriosus (DA) and, accordingly, in its patency. We previously reported...

...Michael Obladen Ductus arteriosus and foramen ovale were described by Galen without understanding their functions. His beliefs in soul localization and spiritization within the left ventricle established religious pneumatology which became a theological need in the Middle Ages. Pulmonary transit...

...Rob M.J. Moonen; Pia Ågren; Angel L. Cogolludo; Francisco Perez Vizcaino; Eduardo Villamor Background: Changes in pH can have profound effects on vascular tone and reactivity, but their influence on the ductus arteriosus (DA) remains unknown. Objective: To analyzethe effects of hypercarbic...

...Regina Bökenkamp; Marco C. DeRuiter; Conny van Munsteren; Adriana C. Gittenberger-de Groot The unique differentiation program of the ductus arteriosus (DA) is essential for its specific task during fetal life and for the adapting circulation after birth. Phenotypic changes occur in the DA during...

...Kazuyoshi Arishima; Masako Yamamoto; Tatsuya Takizawa; Hiroaki Sohmiya; Yasunobu Eguchi; Kohei Shiota This study was conducted to determine whether acute alcohol consumption in near-term pregnant rats results in constriction of the fetal ductus arteriosus (DA). Twenty milliliters per kilogram of 30...

...M.O. Pulkkinen; K. Momma; J. Pulkkinen Progesterone substitution in the rat during pregnancy days 17–21 or administration 6 h before spontaneous delivery constricted the fetal ductus arteriosus. The rapid whole-body freezing technique was used. Indomethacin-induced constriction of the fetal ductus...

... by either conventional ventilation (CV) or high frequency ventilation (HFV) at 15 Hz. The lambs were treated with suspensions of natural sheep surfactant to permit ventilation and survival, and ventilatory settings were adjusted to maintain physiologic blood gas values. The ductus arteriosus was occluded...

...Katsuaki Toyoshima; Kazuo Momma; Toshio Nakanishi Background: Magnesium sulfate (MgSO 4 ) is used therapeutically for eclampsia and tocolysis. Some reports have suggested a relationship between therapeutic MgSO 4 and patent ductus arteriosus (DA) in preterm infants. Objectives: To clarify patent DA...

...Kazuo Momma; Katsuaki Toyoshima; Kiyomi Ito; Kiyoshi Sugiyama; Shinichiro Imamura; Fang Sun; Toshio Nakanishi Background: Indomethacin is used to close the patent ductus arteriosus in premature infants and for tocolysis of preterm labor. Clinically and experimentally, early in utero exposure...