..., a significant growth response was measured (133.2 ± 4.8%). Expression of Ad-AT 2 alone induced a ∼20% increase in total cellular protein content, which was unaffected by addition of AngII. Neither corticosterone (1 µmol/l) nor dexamethasone (1 µmol/l) had any significant effect on the AT 1 - or AT 2 -mediated...

... with high plasma glucocorticoid and adrenocorticotropic hormone levels. Glucocorticoid injections 2 h after birth that elevated plasma corticosterone to high physiological levels for 1-2 additional hours significantly increase plasma glucose levels compared to vehicle-injected controls. These results...

... < 0.001) in the proximal and the distal small bowel. In the duodenum, PGE 2 treatment (4 mg/kg body weight) produced a significant increase in crypt depth (35%, p < 0.001), although villus height was not modified. Serum corticosterone levels were significantly increased in PGE 2 -treated rats...

... through the umbilical vein. Blood samples were collected 15 and 30 min after injection for the determination of corticosterone concentration and the different plasma molecular adrenocorticotropic hormone (ACTH) forms isolated by chromatography on Sephadex G 50 fine. All the plasma samples chromatographed...

...), triglycerides (TRI), corticosterone (CORT), cholesterol (CHOL), and high (HDL) and low (LDL) density lipoproteins. Serum GLU and TRI increased at each sampling day to reach a peak on days 3 and 4, respectively, and then decreased thereafter. However, CHOL, HDL, and LDL decreased sharply by day 1...

...S. Deloff; A. Leprêtre; V. Montel; A. Châtelain The effect of rat atrial natriuretic factor (rANF) on aldosterone and corticosterone secretion was investigated in vivo in 21-day-old rat fetuses injected intravenously through the umbilical vein and in vitro on isolated adrenal cells from 17-, 19...

... Corticosterone Abstract. The present study examined the effects of pentagastrin and adrenalectomy on choline acetyltransferase (ChAT) and acetylcholine esterase (AChE), enzymes which synthe­ size and degrade acetylcholine in the rat gastrointestinal tract. Adrenalectomized and nonadrenalectomized rats, 14 and 21...

...Jean-Paul Dupouy; Alain Chatelain; Françoise Boudouresque; Bernard Conte-Devolx; Charles Oliver Different hormones of the hypothalamo-pituitary-adrenal axis (corticotropin-releasing factor, adrenocorticotropic hormone, corticosterone) were measured in brain pieces (stalk, median eminence...

... for glucocorticoid receptors, as previously suggested, since the corticosterone/progesterone ratio was unchanged in pregnant rats. Liver MT response to food and water deprivation with or without restraint was somewhat different in nulliparous and pregnant rats. Thus, food and water deprivation for 24 h caused higher...

... the adrenal glands of the 5-day-old rats treated with MET contained less corticosterone (determined fluorometrically) than the 5-day-old control and the 10-day-old pups treated also with MET. Furthermore, neonatal MET treatment induced (histamine) stress response by the increase in adrenal corticosterone...

... than in the controls. Peripheral serum testosterone and corticosterone, and testicular testosterone levels were only slightly decreased by the treatment. The changes observed in these neonatal animals suggest a regulatory function for P in the development of the fetal adrenal gland and testis. 17...

... sacrificed on the 20th and 22nd days of pregnancy. DEX reduced adrenal weights and concentration of corticosterone in plasma of the treated females and their fetuses. Fetal body weight was also reduced. However, the lightest adrenal glands were found in fetuses of the DEX 17–18 mothers. Furthermore, the 19...

...M. Roudier; B. Portha; L. Picon In the fetal rat, plasma corticosterone concentration (PCC) decreases dramatically on the 20th day of gestation and remains low until birth even if the parturition is delayed until 23.5 days postcoitus. In the normal term newborn, there is an increase of PCC...

... littermates. At 21 days the smallest adrenals were in the rats treated with metopirone at 7–10 days. Metopirone increased resting and stress levels of adrenal and plasma corticosterone in the 14-day-old rats and the response to stress by the adrenal corticosterone increase in the 21-day-old rats...

.... Litter size Corticosterone Stress Pituitary Adrenal Gonads Rat Biol. Neonate 32: 83-93 (1977) Differential Effect of Pre-and Postnatal Litter Size Reduction on Body Weight and Development of Stress Response in the R at1 K. Milkovic, M. Peruzovic, R. Romic, J. Paunovic and K. Pope Institute...

... days of age, organ weight, intestinal and pancreatic function, and plasma corticosterone levels were analyzed. Moreover, 14-days old pups receiving a single dose of PHA, enterally or parenterally, were sacrificed after 12 h and examined for organ PHA binding using immunohistochemistry. Results: Enteral...

...Annica Sohlström; Christin Carlsson; Kerstin Uvnäs-Moberg The aims of this study were: (1) to assess the effects of maternal undernutrition during pregnancy on adult offspring with regard to growth, body composition and plasma levels of glucose, insulin and corticosterone, and (2) to investigate...

... and aldosterone; fetal insulin and corticosterone levels increased. Maternal diabetes had no effect upon fetal adrenal expression of P450scc mRNA; the abundance of P450c11β mRNA increased, and returned to that of the control gestation upon insulin treatment. P450c11AS mRNA was barely detectable, and decreased...