..., but increase mortality. Inhaled corticosteroids started after the first week of age have little effect, but data are sparse. Systemic corticosteroids started in the first week after birth reduce BPD but increase cerebral palsy. Systemic corticosteroids started after the first week of age reduce both BPD...

... asphyxia and TH, the outcome of 42 infants (gestational age 36.1–42.6 weeks and birth weight 2,280–5,240 g) with proven sepsis ( n = 14) and probable sepsis ( n = 28) was analyzed. Death, cerebral palsy, or a delayed development at 2 years was considered an adverse outcome. Results: Sepsis was caused...

...., cerebral palsy [CP], neurodevelopmental delay) was present in 11 (9%) cases and 20 (9%) controls. No statistically significant differences in outcome were found between cases and controls. Additional MRI was performed in 165/391 infants (42%) and showed additional lesions in 73 (44%) infants that could...

.... Conventional MRI findings were scored with a standardized algorithm and tested using a multivariable regression model to predict neurodevelopmental impairment, defined as one or more of the following at 18-24 months' corrected age: cerebral palsy, bilateral blindness, bilateral deafness requiring amplification...

...Hanna Kallankari; Johanna M. Huusko; Tuula Kaukola; Marja Ojaniemi; Mari Mahlman; Riitta Marttila; Stephen F. Kingsmore; Leena Haataja; Pascal M. Lavoie; Anne Synnes; Mikko Hallman Background: Prematurity and hereditary factors predispose to cerebral palsy (CP). Previously, low cord blood levels...

...Lan-Wan Wang; Yung-Chieh Lin; Shan-Tair Wang; Tsu-Fu Yeh; Chao-Ching Huang; for the Taiwan Premature Infant Developmental Collaborative Study Group Background: Hypoxia/ischemia and inflammation are two major mechanisms for cerebral palsy (CP) in preterm infants. Objective: To investigate whether...

.... This maturational effect is accompanied by a susceptibility of the lung for further postnatal injury, which predisposes for bronchopulmonary dysplasia. Chorioamnionitis is associated with cystic periventricular leukomalacia, intraventricular hemorrhage and cerebral palsy in preterm infants, but its association...

... or neurological problems. Extremely preterm infants Pulmonary function Cerebral palsy Cognitive function © 2010 S. Karger AG, Basel 2010 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized...

... of an increase in cerebral palsy or abnormal neurological examination were partly offset by a trend in the opposite direction in death before late follow-up. Conclusions: The benefits of late dexamethasone may not outweigh actual or potential adverse effects. Given the evidence of both benefits and harms...

... also increased. In the seven trials (921 infants) that reported late outcomes, cerebral palsy and the combined outcome of death or cerebral palsy were significantly more common in those treated with dexamethasone. Conclusions: The benefits of early dexamethasone treatment (≤7 days) to prevent BPD do...

... Bronchopulmonary dysplasia treatment, infants Mortality rate Cerebral palsy formerly Biology of the Neonate Systematic Review and Meta-Analysis Neonatology 2010;98:111 117 DOI: 10.1159/000279992 Published online: February 12, 2010 Postnatal Hydrocortisone for Preventing or Treating Bronchopulmonary Dysplasia...

... cerebral palsy (CP) (p = 0.03 and p = 0.003, respectively). False-positive results were frequent (13 of 17 for SEP1 and 20 of 28 for SEP2). A normal SEP, even when there was periventricular echogenicity on head ultrasound, was associated with a normal outcome in all but 1 instance. SEP1 and SEP2 were less...

... injury Brain damage Cerebral palsy Umbilical cord compression Pregnancy abnormality Biol. Neonate 26: 21-43 (1975) Fetal Asphyxia due to Umbilical Cord Compression Metabolic and Brain Pathologic Consequences Ronald E. M yers Laboratory of Perinatal Physiology, National Institute of Neurological...

... defect Perinatal injury Brain damage Growth retardation Hypotrophy Cerebral palsy Biol. Neonate 22: 253-273 (1973) Perinatal Brain Damage: Porencephaly in a Cynomolgous Monkey R .E . M yers. M arion G. V alerio, D . P. M artin an d K arin B .N elson Laboratory of Perinatal Physiology, National...

... Cerebral palsy formerly Biology of the Neonate 12th Nils W. Svenningsen Memorial Lecture Neonatology 2009;95:342 346 DOI: 10.1159/000209299 Published online: June 4, 2009 Fetal Monitoring during Labor Ingemar Ingemarsson Department of Obstetrics and Gynaecology, Lund University Hospital, Lund, Sweden...

...Outi M. Peltoniemi; Aulikki Lano; Riina Puosi; Anneli Yliherva; Francesco Bonsante; M. Anneli Kari; Mikko Hallman Background: Dexamethasone treatment is associated with an increased risk of cerebral palsy (CP). Early hydrocortisone (HC) treatment may decrease the incidence of bronchopulmonary...

... Neonatal outcome Cerebral palsy 2 10 2008 formerly Biology of the Neonate Review Neonatology 2009;95:6 14 DOI: 10.1159/000151750 Outcomes of Multiplets E.S. Shinwella T. Haklaib S. Eventov-Friedmana aDepartment of Neonatology, Kaplan Medical Center, Rehovot, and Hebrew University...

..., periventricular leukomalacia brain damage Blood-brain barrier Cerebral palsy Developmental biology Erythropoietin Hypoxic-ischemic brain injury Perinatal period Periventricular leukomalacia White matter damage formerly Biology of the Neonate Original Paper Neonatology 2008;94:255 266 DOI: 10.1159...

... of change in practice with the use of postnatal corticosteroids over an 8-year period in extremely preterm babies on the incidence of chronic lung disease (CLD) and cerebral palsy at 1 year of age. Methods: Babies of birth weight <1,000 g or gestational age <28 weeks admitted from 1997 to 2004 were...

... by estimating the number needed to treat (NNT) and the number needed to harm (NNH) for the outcome of cerebral palsy (CP). When given prophylactically during the first 4 days of life, corticosteroids increase the risk of CP (NNH 22; 95% CI: 12–133). When prescribed between days 7 and 14, corticosteroids reduce...