Hypothyroxinemia in preterm infants without congenital hypothyroidism is associated with developmental delay. Longitudinal information on thyroid function in very-low-birth-weight (VLBW, <1,500 g birth weight) infants is limited: we present data on thyroid function in sick and healthy VLBW infants until 6 weeks of age. Free T4 and TSH levels routinely obtained on days 14–21 and days 35–49 in 92 consecutive VLBW infants were correlated retrospectively with neonatal morbidity. Free T4 levels were positively correlated with gestational age; an independent effect of neonatal disease on thyroid function was not detectable.

Keywords:
Preterm infant, Thyroid, Free thyroxine, Thyrotropin, Chronic lung disease of prematurity
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© 2001 S. Karger AG, Basel
2001
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