The placental transfer of retinol and β-carotene was assessed based on maternal serum, cord serum and placental levels at term parturition in women with adequate (n = 15; serum retinol > 20 μg/dl) and subadequate (n = 16; serum retinol ≤ 20 μg/dl) vitamin-A status. There was no difference in retinol and β-carotene levels in placenta and cord serum between these groups. However, differences in the relation of maternal, placental and cord blood components were observed between women with adequate and subadequate vitamin-A status. In women with subadequate status, circulating fetal retinol levels correlated with placental retinol levels, and maternal serum β-carotene correlated with placental retinol. Within this group, maternal serum β-carotene and cord serum retinol correlated significantly in women with serum retinol levels lower than 15 μg/dl. These results suggest that β-carotene may be a precursor of retinol in placenta and that this conversion may depend on the nutritional status of the mother, being particularly effective in a more depleted state.

Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.