We have used a modified photodiode method to measure ciliary beat frequency of human neonatal cilia, and have developed techniques to allow similar measurements of rat brain cilial function. The effect of temperature change, within the physiological range, on neonatal human respiratory cilia and neonatal rat brain cilia was studied. The mean (SD) ciliary beat frequency of neonatal respiratory cilia at body temperature was 14 (1.1) Hz and that of rat brain cilia 18.9 (1.3) Hz. Respiratory cilial beat frequency decreased by 9.1% and brain cilia by 13% on cooling to 32 °C compared to normal body temperature. Beat frequency increased by 8.5% in respiratory samples and by 12% in brain samples on warming to 40 °C compared to the frequency at normal body temperature. The Q10 of human neonatal respiratory cilia was 1.2 and that of rat brain cilia 1.3.

This content is only available via PDF.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.