Lipase activities measured at pH 4 and 8 were determined in the placentas of rats subjected to undernutrition or uterine artery ligation. The fetal lipid content following maternal undernutrition was also determined. The placental lipase activity (per gram placenta) measured at pH 8 (placental lipoprotein lipase) remained unchanged, whilst the activity of the intracellular lipase (per gram placenta) measured at pH 4 was significantly less than in the control group (21 % lower in maternal undernutrition and 16 % lower after uterine artery ligation). Although placentas and fetuses were significantly lighter in both situations as compared to controls (well-nourished or sham operated, respectively), fetal lipid content in maternal undernutrition was only reduced to a degree concomitant with the decrease in fetal weight. We therefore conclude that the intracellular lipase may not have an important role in the provision of free fatty acids in undernutrition.

Keywords:
Placenta, Lipase, Undernutrition
This content is only available via PDF.
© 1991 S. Karger AG, Basel
1991
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.