...Scott T. Cain; Michael J. Owens; Charles B. Nemeroff Corticotropin-releasing-factor-like immunoreactivity (CRF-LI) was measured in a number of subcellular fractions from rat brain using a highly sensitive and specific radioimmunoassay. CRF-LI was highly enriched in the crude synaptosomal...

... that this fraction was composed of mitochondria plus synaptosomes (pinched-off nerve terminals). To further explore the location of aromatase in the 11,000 g fraction, P2 was exposed to hypotonic buffer, a treatment known to cause lysis of synaptosomes, and then separated into three fractions P2a (11,000 g pellet...

...Lucio Annunziato; Pierre Leblanc; Claude Kordon; Richard I. Weiner A comparison of the kinetics of dopamine uptake was made in synaptosomal preparations of the median eminence, striatum and olfactory tubercle. Double reciprocal Lineweaver-Burk plots of the initial velocity versus the concentration...

...Lucio Annunziato; Richard I. Weiner The kinetics of dopamine (DA) uptake were studied in synaptosomal preparations of the neurointermediate lobe (NIL) of the pituitary gland, a region containing the terminals of the tuberoinfundibular dopaminergic neurons. Lineweaver-Burk plots of the initial...

...E.A. Linton; G.W. Bennett; S.A. Whitehead The possible role of prostaglandins (PGs) in the hypothalamic control of ovulation has been investigated by studying the effects of indomethacin (ID) and PGs on the release of luteinizing hormone-releasing hormone (LHRH) from hypothalamic synaptosomes...

...Ana Duarte; Maria Santos; Raquel Seiça; Catarina Resende de Oliveira It has been suggested that increased oxidative stress might be involved in the pathophysiology of diabetic complications. In this study, we investigated the effect of diabetes on the susceptibility of synaptosomes to oxidative...