... as during diapause, a reversible state of blastocyst development arrest that shares metabolic, transcriptomic, and proteomic similarities with pluripotent stem cells in the naïve state. Thus, we analyzed the role of the hormone during those processes, which involve the regulation of its receptor and several...

...Montserrat Garcia-Lavandeira; Esther Diaz-Rodriguez; Dilek Bahar; Angela R. Garcia-Rendueles; Joana S. Rodrigues; Carlos Dieguez; Clara V. Alvarez The recent demonstration using genetic tracing that in the adult pituitary stem cells are normally recruited from the niche in the marginal zone...

... understood. It was proposed that adult stem cells direct the generation of newborn cells with a hormonal phenotype according to the physiological requirements. However, only in recent years adult pituitary stem cells have begun to be phenotypically characterized in several studies that identified multiple...

...Hugo Vankelecom Tissue-specific stem cells are uncovered in a growing number of organs by their molecular expression profile and their potential for self-renewal, multipotent differentiation and tissue regeneration. Whether the pituitary gland also contains a pool of versatile ’master’ cells...