... elicited a 41% depletion of NPY-LI 2 h after insulin injection, while the concentrations of PACAP-27-LI remained unchanged. Two days after reserpine administration the stores of PACAP-27-LI and NPY-LI were depleted by 62 and 41%, respectively. Two days later, the concentrations of NPY-LI were increased...

...Martin T. Lowy The effect of the biogenic amine depleting drug, reserpine, on the concentration of type II corticosteroid receptors (i.e., glucocorticoid receptors) in neuronal (hippocampus, frontal cortex, hypothalamus), lymphoid (circulating lymphocytes, spleen, thymus) and pituitary tissues...

...Sophie Papas; Seon Ho Shin; Marc Claude Obonsawin Met-enkephalin concentrations in the anterior pituitary gland were shown to decline dramatically within the first 24 h after reserpine treatment, with effects apparent as early as 6 h. This was followed by subsequent repletion and late augmentation...

...–6 days with various doses of the following drugs, alone or in combination: haloperidol (a dopamine receptor blocker), reserpine (a catecholamine depleting agent), and bromocriptine (a dopamine receptor agonist). Neurointermediate lobe () homogenates were prepared. Following activation of latent...

... but not kallikrein substrates. This study examined whether any of the pituitary proteases are regulated by dopaminergic mechanisms. Ovariectomized female rats were treated for 5–10 days with reserpine (a catecholamine depleting agent), haloperidol (a dopamine receptor blocker) or bromocriptine (a dopamine receptor...

... at 14.00. Following an intravenous administration of FK 33–824 (10 μg/100 g b.w.), there was an abrupt increase in plasma GH, which was significantly suppressed by naloxone (125 μg/ 100 g b.w., i.v.), a specific opiate antagonist. Pretreatment with reserpine (1 mg/100 g b.w., i.p.) abolished not only...

...S. Eden; E. Eriksson; J.B. Martin; K. Modigh The effects of adrenergic receptor agonists on GH secretion were studied in adult, male rats pretreated with reserpine and somatostatin antiserum. Frequent blood samples were obtained from intra-aortic cannulae. Plasma GH was determined...

...Rex D. Stith; Daniel P. Weingarten Cats were injected intraperitoneally with reserpine (5 mg/kg) or saline and sacrificed 16 h later. Hypothalamic and hippocampal cytosols were assayed for the kinetics of 3 H-dexamethasone ( 3 H-DM) binding. A parallel series was performed in which saline-injected...

...M. Nishizuka 82% of female mice, that had received a single injection of 50 µ g testosterone propionate (TP) at 4 days of age, became persistent estrous by 90 days. If 50 µ g pentobarbital or 10 µ g reserpine was given simultaneously with TP, the incidence of hypothalamic masculinizatîon...

... not affect the levels of the 3 hormones. Pre-treatment of proestrous rats with reserpine markedly reduced the ether-induced depression of the PRLN level, and prevented the proestrous LH ‘surge’ and ovulation, whereas in the diestrous rats it increased the PRLN level about 20-fold, without affecting the lack...

... (DA), and propranolol did not. The augmented response was similar to that observed following the daily administration of reserpine (0.25 mg/kg, s.c). The response to this dose of reserpine was blocked by the simultaneous administration of a low dose of dexamethasone (14 µ g/kg, s.c). Augmentation...

...U. Scapagnini; L. Annunziato; G. Di Renzo; G. Lombardi; P. Preziosi Daily i.p. injection of reserpine for 9 days strongly depletes hypothalamic norepinephrine (NE); after an initial activation, adrenocortical function returns to control values by the 5th day. Tyrosine hydroxylase (TH) activity...

...R.I. Weiner; W.F. Ganong The effects of reserpine and α-methyl- p -tyrosine on the occurrence of vaginal opening were studied in rats. Reserpine decreased hypothalamic norepinephrine content and delayed vaginal opening. However, it also caused a decrease in the rate of body weight gain...

...A.N. Bhattacharya; B.H. Marks The effect of α-methyl tyrosine or p-chlorophenylalanine pre-treatment of rats was tested on the ability to respond to anacute stress, a chronic stress, and to reserpine-induced ACTH hypersecretion. This pretreatment had no effect on any of these pituitary responses...

...E.S. France A single injection of 62.5 µg reserpine inhibits ovulation induced in intact immature rats by administration of pregnant mare’s serum (PMS) and human chorionic gonadotrophin (HCG) when reserpine is given ½ to 6½ h before HCG. Increases or decreases in the amount of HCG are not reflected...

...S. Taleisnik; Maria E. Tomatis; Maria E. Celis Suppression of the adrenergic system by injection of reserpine (0.2 mg/kg for 2 days) into male rats resulted in a decrease of the pituitary MSH content. The same effect was observed 30, 60, or 120 min after intraperitoneal administration of dibenamine...